It is generally believed that the occlusion of a nondominant right coronary artery is not associated with significant consequences. Atherosclerotic disease of non-dominant right coronary in the absence of significant left coronary artery disease is rare, and the prevalence is substantially lower as compared to dominant Right Coronary Artery. We report a case of a young male presenting with acute coronary syndrome and hemodynamically significant atrial fibrillation. Coronary angiography showed thrombotic occlusion of the nondominant right coronary artery. After the stenting of this artery, the patient improved hemodynamically with complete resolution of ECG changes.