Isolated Pancreatic Tuberculosis Mimicking Pancreatic Cancer: A Diagnostic Challenge

Bhurwal, Abhishek; Haq, Muhammad Masoodul; Sapru, Sunil; Tortora, Matthew; Ramasamy, Dhanasekaran

doi:10.1155/2018/7871503

Cited by 6 publications

(3 citation statements)

References 16 publications

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“…Pancreatic TB usually presents with nonspecific symptoms such as abdominal pain, jaundice, vomiting, anorexia, or weight loss [3]. CT and MRI frequently show a pancreatic mass and almost half the cases exhibit involvement of peripancreatic lymph nodes [4].…”

Section: Discussionmentioning

confidence: 99%

Pancreatic Mass: Include Tuberculosis in the Differential Diagnosis

Sohni¹

2021

Cureus

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Although abdominal tuberculosis (TB) is quite prevalent in endemic regions, involvement of the pancreas is considerably rare. We describe a case of pancreatic TB presenting as a pancreatic mass in a patient with abdominal pain and jaundice. Due to the similar presentation, it can easily be misinterpreted as a pancreatic neoplasm. Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) can help confirm the diagnosis in such cases by providing histopathological evidence of Mycobacterium tuberculosis infection. The patient made a remarkable recovery post anti-tuberculous therapy (ATT) initiation. This exceptional response of pancreatic TB to conservative management makes it imperative that the condition be diagnosed promptly to avoid any futile surgical interventions and associated complications. This can only be achieved if clinicians are aware of the diagnostic possibility of pancreatic TB presenting as a mass in the pancreas.

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Section: Discussionmentioning

confidence: 99%

Pancreatic Mass: Include Tuberculosis in the Differential Diagnosis

Sohni¹

2021

Cureus

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“…Even in parts of the world where tuberculosis (TB) is highly prevalent, isolated pancreatic TB is a rare entity, often presenting as a diagnostic challenge [ 1 ]. Pancreatic TB commonly presents as a mass lesion causing compression of local structures and mimics pancreatic malignancy, both clinically and radiologically [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

“…Pancreatic TB commonly presents as a mass lesion causing compression of local structures and mimics pancreatic malignancy, both clinically and radiologically [ 2 ]. Endoscopic ultrasound with fine-needle aspiration (EUS-FNA) can provide an accurate diagnosis [ 1 ]. Often the diagnosis is made postoperatively (on histopathology after pancreatic mass removal) due to the low index of suspicion of this entity and masquerading of its symptoms as more common pancreatic conditions.…”

Section: Introductionmentioning

confidence: 99%

Pancreatic Tuberculosis: A Diagnostic Dilemma

Haseeb

Bilal²,

Bokhari

et al. 2021

Cureus

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Despite the high prevalence of tuberculosis (TB) in developing countries, pancreatic TB remains a rare disease. Pancreatic TB usually presents as fever, night sweats, and abdominal pain in an immunocompromised individual. We present a case of a patient with end-stage renal disease undergoing pre-transplant workup who had an incidental finding of a pancreatic mass and necrotic peri-pancreatic lymph nodes on a CT scan. The patient was diagnosed via endoscopic ultrasound-guided biopsy as pancreatic TB. Anti-TB therapy was started with positive results.

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Current role of endoscopic ultrasound for gastrointestinal and abdominal tuberculosis

et al. 2022

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A high incidence of tuberculosis (TB), especially in endemic countries, makes this infectious disease a concern. Abdominal TB contributes to 10% of extrapulmonary TB. Due to nonspecific clinical, radiological, and endoscopic findings, diagnosing abdominal TB continues to be a challenge. Hence, a precise diagnosis is needed. The diagnosis of gastrointestinal disease using endoscopic ultrasound (EUS) is often performed due to its high resolution and ability to provide a real-time visual representation of the gastrointestinal tract and extramural structures. EUS-guided fine-needle aspiration (FNA) and fineneedle biopsy (FNB) have helped diagnose TB as they offer an adequate specimen for cytology or histopathological examination. This method is considered safer, more effective, and more efficient. The capacity of EUS to diagnose abdominal TB based on the affected organs was examined via a literature search. We reviewed the role of EUS in diagnosing esophageal, gastric, pancreatic, peripancreatic, hepatosplenic, peritoneal, and intestinal TB. Generally, EUS aids in diagnosing abdominal TB. In some organs, it is superior to other diagnostic modalities. However, further examinations, such as cytology or histopathology and microbial, are still needed. We also studied the roles of EUS-FNA and EUS-FNB. EUS-FNA has shown a high diagnostic yield in esophageal (94.3-100%), pancreatic and peripancreatic (76.2%), and intestinal TB (84.1%). As minimally invasive methods, EUS-FNA and EUS-FNB can successfully provide sufficient samples. EUS is a functional diagnostic modality for abdominal TB. EUS-FNA and EUS-FNB provide sufficient samples safely and efficiently for further cytology, histopathology, and microbial examinations. Esophageal tuberculosisEsophageal TB is uncommon and has nonspecific clinical, laboratory, radiological, and endoscopic features. With prevalence

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Isolated Pancreatic Tuberculosis Mimicking Pancreatic Cancer: A Diagnostic Challenge

Cited by 6 publications

References 16 publications

Pancreatic Mass: Include Tuberculosis in the Differential Diagnosis

Pancreatic Mass: Include Tuberculosis in the Differential Diagnosis

Pancreatic Tuberculosis: A Diagnostic Dilemma

Current role of endoscopic ultrasound for gastrointestinal and abdominal tuberculosis

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