“…In 30%-35% of cases, they involve the skull base, most frequently at the spheno-occipital level. These tumors normally grow slowly and cause symptoms related to the mass influence on nearby structures (brainstem, cranial nerves, nasopharynx, spinal cord) [ 2 , 3 ]. Since chordomas arise in bone, they are usually extradural and cause local bone destruction.…”