Isolated third nerve palsy complicating Rickettsial fever: A rare neurological complication

Premathilake, P. N. S.; Kularatne, W. K. S.; Senadhira, S. D. N.

doi:10.4038/jpgim.8195

Search citation statements

Order By: Relevance

Paper Sections

Select...

Discussion1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2021

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

(1 citation statement)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…There have been two other cases of rickettsial infection with isolated third cranial nerve palsy reported [5,8]. Similar to our case, these two patients presented with fever, rash, and unilateral left oculomotor nerve palsy, but eschar was absent.…”

Section: Discussionsupporting

confidence: 86%

A rare case of rickettsial fever with isolated third cranial nerve palsy causing hemophagocytic lymphohistiocytosis

Arumilli¹,

Revappa²,

Rao³

et al. 2021

Indian J Case Reports

View full text Add to dashboard Cite

Rickettsial infections are being increasingly diagnosed in the Indian subcontinent with the advent of affordable and sensitive diagnostic techniques. Rickettsial infections are sometimes complicated by the development of secondary hemophagocytic lymphohistiocytosis (HLH) which is life-threatening unless identified early and treated. Here, we describe a case of rickettsial fever in a 41-year-old male who presented with fever, skin rash, and neurological obtundation, complicated by both third cranial nerve palsy and HLH. The patient showed a good recovery in sensorium with intravenous doxycycline and dexamethasone, although the oculomotor nerve palsy persisted for about two months after discharge. This case highlights the need to initiate treatment for rickettsial fever and HLH on clinical grounds before waiting for confirmation by laboratory tests.

show abstract

Section: Discussionsupporting

confidence: 86%