Isolated Ventricular Non-Compaction in Adults With Idiopathic Cardiomyopathy: Cardiac Magnetic Resonance and Pathologic Characterization of the Anomaly

Left Ventricular Non-Compaction: Mid-myocardial Distribution of Late Gadolinium Enhancement in Compacted Segments

“…These data are in agreement with previous CMR studies [6,7,11,14] and myocardial tissue samples [17,18] which confirmed the heterogeneous distribution of myocardial fibrosis in patients with LVNC.…”

Reversible isolated left ventricular non-compaction?

“…Because of its better spatial resolution, CMR detected pronounced trabeculations and recesses that are compatible with LVNC. The better diagnostic utility of CMR as compared with echocardiography has been reported previously [5]. It is generally thought that LVNC leads to a progressive dilated cardiomyopathy but our case suggests that LVNC can be either reversible or may have a dynamic course, or that current morphological criteria occasionally allow to misclassify a transient cardiomyopathy as noncompaction.…”

Isolated left ventricular non-compaction controversies in diagnostic criteria, adverse outcomes and management

“…Additional morphological consideration for diagnosis of LVNC that we have consistently noted in our lab, although not formally published, includes thinned compacted epicardial layers at the sites of non-compaction as previously described39 (Jenni et al 's criteria), as well as an abrupt transition from normal to ‘non-compacted’ segments (figure 2, C1–2). However, beyond morphology, CMR provides opportunities for more comprehensive myocardial characterisation.…”