“…A wide variety of membrane mutants have been isolated, including cells resistant to fusogenic agents (Stadler and Hanser, 1980), lectins (Stanley, 1980), cells possessing altered adhesive properties (Atherly et al, 1977), cells expressing a temperature-sensitive defect in endocytosis (Silberstein et al, 1975) and cells resistant to membrane anesthetics (Vaughan and Stadler, 1980)i 4. Utility of membrane mutants in studying membrane structure and function Membrane mutants have been used to study a number of cellular functions dependent on normal membrane organization and structure.…”