2018
DOI: 10.3390/molecules23092400
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Isolation and Identification of Benzochroman and Acylglycerols from Massa Medicata Fermentata and Their Inhibitory Effects on LPS-Stimulated Cytokine Production in Bone Marrow-Derived Dendritic Cells

Abstract: Massa Medicata Fermentata (MMF), known as Shenqu, is an important traditional Chinese medicine widely used to treat indigestion, vomiting, and diarrhea. In this study, a new benzochroman, 3(S)-3,4-dihydro-5,10-di-β-d-glucopyranoside-2,2-dimethyl-2H-naphtho(2,3-b)pyran-3-ol (1), and five known galactosyl acylglycerols (2–6) were isolated from a methanol extract from MMF. In addition, their chemical structures were determined by chemical and spectroscopic methods, which were compared with the previously reported… Show more

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Cited by 5 publications
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“…Currently, pathogen identification and therapeutic approaches play important roles in controlling infections. However, the traditional gold standard diagnostic method, i.e., culturing and colony counting, is limited by long waiting times (and thus wasted time), as culturing of most clinical bacterial pathogens requires 1–2 days (much longer times are required for several bacterial species), and low efficiency due to contamination and significant experimental error [4,5,6]. Rapid and effective detection technologies are especially and urgently needed for an early-stage diagnosis, at which time there are low concentrations of the target pathogen.…”
Section: Introductionmentioning
confidence: 99%
“…Currently, pathogen identification and therapeutic approaches play important roles in controlling infections. However, the traditional gold standard diagnostic method, i.e., culturing and colony counting, is limited by long waiting times (and thus wasted time), as culturing of most clinical bacterial pathogens requires 1–2 days (much longer times are required for several bacterial species), and low efficiency due to contamination and significant experimental error [4,5,6]. Rapid and effective detection technologies are especially and urgently needed for an early-stage diagnosis, at which time there are low concentrations of the target pathogen.…”
Section: Introductionmentioning
confidence: 99%