Isolation and structural identification of two bioactive phenazines from Streptomyces griseoluteus P510

Luo, Qin; Hu, Hongbo; Peng, Huasong; Zhang, Xuehong; Wang, Wei

doi:10.1016/j.cjche.2015.01.001

Cited by 13 publications

(13 citation statements)

References 35 publications

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“…Generally, PGPR benefit plant growth either by assisting in nutrient availability (nitrogen, phosphorus, and iron) or by producing phytohormones such as indole acetic acid (IAA) [1]. PGPR can also indirectly help plants to withstand stress (biotic or abiotic) by reducing ethylene levels, through production of enzyme 1-aminocyclopropane-1-carboxylic acid deaminase (ACC deaminase) [2,3]; by locally producing antagonists to soil-borne pathogens; or by inducing systemic resistance (ISR) through plant recognition of microorganismassociated molecular patterns (MAMPs) [4,5]. Indeed, PGPR may use one or a combination of these mechanisms and act as biofertilizers, phytostimulators, and biocontrol agents in the rhizosphere where they are established [6,7].…”

Section: Introductionmentioning

confidence: 99%

“…There is also great interest in these bacteria due to their potential to produce antimicrobial metabolites such as phenazines Responsible Editor: Luc F.M. Rouws [4,10]. Strains of Streptomyces species originating from an Araucaria forest were characterized as PGPR, based on their capacity for IAA production [11], phosphate solubilization, antibiosis, and production of siderophores [12].…”

Section: Introductionmentioning

confidence: 99%

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Streptomyces sp. CLV45 from Fabaceae rhizosphere benefits growth of soybean plants

et al. 2020

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Plant growth-promoting bacteria such as Streptomyces are an attractive alternative for increasing the sustainability of agricultural systems. In this study, Streptomyces isolates obtained from rhizosphere soil of plants in the family Fabaceae were characterized for their plant growth-promoting traits, including the production of siderophores, 1-aminocyclopropane-1-carboxylate (ACC) deaminase, indole-3-acetic acid (IAA), and phenazines. Soybean seeds were bacterized with selected isolates to test growth promotion. All isolates produced IAA, and the isolate CLV45 was the most efficient, reaching 398.53 mg of IAA per gram of cells. CLV41, CLV45, and CLV46 showed high activity for ACC deaminase whereas CLV42, CLV44, and CLV46 were efficient in siderophore production. Pyocyanin was detected in all isolates; CLV41, CLV43, and CLV45 produced phenazinecarboxylic acid as well. Selected for IAA and ACC deaminase production combined with production of siderophores and phenazines, CLV42, CLV44, and CLV45 were tested for their growth promotion potential. Seed bacterization with CLV45 resulted in plants with increased shoot growth (36.63%) and dry mass (17.97%) compared to control plants. Results suggest that moderate or high levels of auxin and ACC deaminase production by the isolate CLV45 positively affected the growth of soybean plants, making it a strong candidate for further studies on biofertilizer formulation.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Streptomyces sp. CLV45 from Fabaceae rhizosphere benefits growth of soybean plants

et al. 2020

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“…(13). These include S. griseoluteus (14), S. kebangsaanensis (13), S. lomondensis (15), S. anulatus (16), S. niveus (17) and several other species (14,18,19). Luo et al (14) also noted that members of Streptomyces have commonly been used as a source of various phenazines complex such as griseolutein, phenacetin, lomofungin, and 5,10-dihydrophenazine.…”

Section: Introductionmentioning

confidence: 99%

Isolation and structure elucidation of phenazine derivative from Streptomyces sp. strain UICC B-92 isolated from Neesia altissima (Malvaceae)

Pratiwi¹,

Hidayat²,

Hanafi³

et al. 2020

IJM

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Background and Objectives: Endophytic actinomycetes have been known as a promising source for new antibiotics discov- ery against susceptible and resistant forms of pathogenic microorganisms. This study was aimed at determining antibacterial compound from Streptomyces sp. strain B-92 isolated from a medicinal plant Neesia altissima. Materials and Methods: Streptomyces sp. strain UICC B-92 was endophytic actinomycetes of N. altissima that obtained from Universitas Indonesia Culture Collection (UICC). Isolation and determination of bioactive compound were carried out using thin layer chromatography (TLC), nuclear magnetic resonance spectroscopy (NMR), and liquid chromatography mass spectrometry (LC-MS) analyses. An in vitro antibacterial assay of pure bioactive compound from the endophytic actinomycetes strain was performed against Bacillus cereus strain ATCC 10876, Escherichia coli strain ATCC 25922, Salmonella typhimurium strain ATCC 25241, Shigella flexneri strain ATCC 12022 and Staphylococcus aureus strain ATCC 25923. Results: The bioactive compound was identified as 4-((3S,4R,5S)-3,4,5-trihydroxy-6-(hydroxymethyl) tetrahydro-2H- pyran-2-yloxy) phenazine-1-carboxylic acid. In vitro antimicrobial assay showed that bioactive compound of Streptomyces sp. strain UICC B-92 exhibited antagonistic activities against two Gram-positive bacteria, viz, B. cereus strain ATCC 10876 and S. aureus strain ATCC 25923. Conclusion: The findings of this research showed that, bioactive compound of Streptomyces sp. strain UICC B-92 is sug- gested a new compound based on glycoside structure and its position.

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“…Phenazines, known since the beginning of 19th century, represent an important class of heterocycles showing a great potential as bioactive molecules and as organic-based semiconducting materials. As an example, phenazines, isolated from Pseudomonas, Streptomyces and from soil or marine organisms manifest important biological properties including antibiotic, antitumor, antimalaria and antiparasitic activities [1][2][3] and recently, it is also reported their biofilm eradication properties in the treatment of antibiotic resistant bacteria. 4 In addition, fluorinated phenazines have received particular attention since they present interesting HOMO and LUMO energy levels respect to the hydrogenated counterpart 5,6 and have been proposed as n-type semiconductors potentially exploitable for developing new organic light emitting diode (OLED) and organic field effect transistor (OFET) devices.…”

Section: Introductionmentioning

confidence: 99%

Fluorine substituted non-symmetric phenazines: a new synthetic protocol from polyfluorinated azobenzenes

Vaghi¹,

Coletta²,

Coghi³

et al. 2019

Arkivoc

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A high ortho regioselectivity in nucleophilic aromatic substitution in low polar solvents is reported in the reaction of polyfluorinated azobenzenes with anilines. o-Anilino substituted derivatives could be easily transformed into non-symmetric phenazines by acid catalyzed electrocyclization. Phenazines are interesting compounds for their important properties as bioactive molecules. In addition, these fluorinated phenazines manifest interesting spectroscopic and electronic properties that make them candidates for n-type organic semiconductor. Furthermore, the prepared phenazines show reversible reduction with the LUMO and HOMO energy level controlled by the electronic nature of the substituent on the non-fluorinated ring of the system.

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Isolation and structural identification of two bioactive phenazines from Streptomyces griseoluteus P510

Cited by 13 publications

References 35 publications

Streptomyces sp. CLV45 from Fabaceae rhizosphere benefits growth of soybean plants

Streptomyces sp. CLV45 from Fabaceae rhizosphere benefits growth of soybean plants

Isolation and structure elucidation of phenazine derivative from Streptomyces sp. strain UICC B-92 isolated from Neesia altissima (Malvaceae)

Fluorine substituted non-symmetric phenazines: a new synthetic protocol from polyfluorinated azobenzenes

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