1973
DOI: 10.1016/0040-4020(73)80239-x
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Isolation and synthesis of glutamine and glutarimide derivatives fromCroton humilis

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1974
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Cited by 11 publications
(6 citation statements)
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“…As far as we know, there has been only one report on the synthesis of a lower homologue of julocrotine ( 1 ), using harsh reaction conditions. In view of the importance of glutarimide alkaloids and the promising findings that 1 inhibits the growth of parasites such as L. amazonensis , the need to develop practical methodology for the synthesis of julocrotine and its derivatives was obvious.…”
mentioning
confidence: 99%
“…As far as we know, there has been only one report on the synthesis of a lower homologue of julocrotine ( 1 ), using harsh reaction conditions. In view of the importance of glutarimide alkaloids and the promising findings that 1 inhibits the growth of parasites such as L. amazonensis , the need to develop practical methodology for the synthesis of julocrotine and its derivatives was obvious.…”
mentioning
confidence: 99%
“…Lunaria annua [10,240] Croton humilis [239] Croton humilis [239] Staphylea pinnata seeds; Hemerocallis fulva [193];…”
Section: H Nmentioning
confidence: 99%
“…[7] Glutarimide alkaloids are an important class of natural products. [10] In 2011, a six step synthesis starting from L-glutamic acid was described. [8] The structure of julocrotine was elucidated in 1961 with a series of degradation reactions [9] and a report in 1974 showed the synthesis of a lower homologue using harsh conditions.…”
Section: Introductionmentioning
confidence: 99%