Isolation, characterization, and distribution of two cDNAs encoding for growth hormone receptor in rainbow trout (Oncorhynchus mykiss)

Very, Nicole M.; Kittilson, Jeffrey D.; Norbeck, Lindsey A.; Sheridan, Mark A.

doi:10.1016/j.cbpc.2004.12.008

Cited by 86 publications

(57 citation statements)

References 23 publications

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“…In the examined tissues except for the pronephros, gonad, spleen and pituitary, the expression of GHR 1 was higher than GHR 2, which was consistent with the findings in black sea bream (Acanthopagrus schlegeli) (Tse et al, 2003) and rainbow trout (O. mykiss) (Very et al, 2005), while the opposite result was found in gilthead sea bream (Sparus aurata) (Saera-Vila et al, 2005) and orange-spotted grouper (Epinephelus coioides) (Li et al, 2007). Both of the GHRs were expressed at 2 hpf (the multicellular stage), a similar result was found in Nile tilapia (O. niloticus) (Ma et al, 2007), but GHR 2 was not detected in Japanese eel (A. japonica) at this stage (Ozaki et al, 2006), which was probably caused by maternal GH mRNA from ovum.…”

Section: Discussionsupporting

confidence: 89%

“…The predicted primary amino acid sequences, domain structure, positions of cysteine residues and N-glycosylation sites of GHRs, IGFs and MSTNs were highly conserved ( Saera-Vila et al, 2005), suggesting that they also contained similar secondary and tertiary structures. In the M. amblycephala genome, two GHR genes were found, which was the case in the other fish species, such as zebrafish (Danio rerio) (Di Prinzio et al, 2010), Nile tilapia (Oreochromis niloticus) (Ma et al, 2007), rainbow trout (Oncorhynchus mykiss) (Very et al, 2005) and Japanese eel (Anguilla japonica) (Ozaki et al, 2006). However, in grass carp (C. idella) (Ho et al, 1991), only one GHR gene was found.…”

Section: Discussionmentioning

confidence: 98%

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Characterization of GHRs, IGFs and MSTNs, and analysis of their expression relationships in blunt snout bream, Megalobrama amblycephala

Zeng

Liu

Wang

et al. 2014

Gene

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Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 98%

Characterization of GHRs, IGFs and MSTNs, and analysis of their expression relationships in blunt snout bream, Megalobrama amblycephala

Zeng

Liu

Wang

et al. 2014

Gene

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“…The additional polyploidization in salmonids (Moghadam et al 2005) and a possible loss of GHR in turbot (Saera-Vila et al 2005) makes generalizations about the overall hormone receptor relationships in teleosts difficult. These inconsistent hormone receptor sets and their distinctive expression patterns and functional diversifications (e.g., Fukada et al 2004;Zhu et al 2004;Fukada et al 2005;Fukamachi et al 2005;Saera-Vila et al 2005;Very et al 2005;Jiao et al 2006;Ozaki et al 2006;Zhu et al 2007) would indicate that the in vivo roles of these orthologous genes are not necessarily identical in all teleost species. Our results aid in the clarification of the evolutionary histories of these hormones and receptors.…”

Section: Ancestral Receptor For Slmentioning

confidence: 99%

Evolution of Receptors for Growth Hormone and Somatolactin in Fish and Land Vertebrates: Lessons from the Lungfish and Sturgeon Orthologues

Fukamachi

Meyer

2007

J Mol Evol

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Two cognate hormones, growth hormone (GH) and somatolactin (SL), control several important physiological processes in vertebrates. Knowledge about GH and its receptor (GHR) has accumulated over the last decades. However, much less is known about SL and its receptor (SLR). SL is found only in fish (including lungfish), suggesting that it was present in the common ancestor of vertebrates, but was lost secondarily in the lineage leading to land vertebrates after the lungfish branched off. SLR was suggested to be a duplicated copy of GHR acquired only in teleosts via the fish-specific genome duplication (FSGD). This scenario (i.e., the existence of SL but not SLR in the vertebrate ancestors) is intriguing but contested. In this study, we first evaluated the plausibility of this scenario through synteny analyses and found that the loci for GHR and SLR are located in syntenic genomic positions, whereas the loci for GH and SL are not. Next, we cloned GHRs of lungfish and sturgeon, which possess SL but did not undergo the FSGD (i.e., they should not possess SLR). Their phylogenetic positions in the GHR/SLR gene tree further support the fish-specific scenario for the GHR SLR duplication. Interestingly, their sequences share greater similarity with teleost SLRs and reptilian/amphibian GHRs than with the GHRs of mammals, birds, and teleosts. On the basis of these results, we discuss the validity of the nomenclature of the teleost-specific copy of GHR as SLR and an ancestral receptor(s) for SL before the evolution of SLR during the FSGD.

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“…The fish GHR gene has been successfully cloned and characterized in several fish species such as gilthead sea bream (Sparus aurata) [7], Atlantic (Salmo salar) and masu salmon (Oncorhynchus masou) [8], and rainbow trout (Onchorhynchus mykiss) [9]. Significant associations have been observed between GHR gene polymorphism and growth rates by PCR restriction fragment polymorphism (RFLP) marker (using four restriction enzymes) in 353 individual Cyprinus carpio fish [10].…”

Section: Introductionmentioning

confidence: 99%

Growth Parameters Evaluation and Identification of Growth Hormone Receptor Gene Polymorphisms in Various Strains of Rainbow Trout Oncorhynchus mykiss

Gorji¹,

Rahmani²

2016

J Aquac Res Development

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In the present study, polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) and restriction fragment length polymorphism (RFLP) methods were compared to analyze the polymorphism of growth hormone receptor (GHR) gene in French, Iranian and Danish strains of Oncorhynchus mykiss. A monomorphic SSCP pattern of AA genotype in the French and Iranian strains and a dimorphic AA and AB genotype in the Danish strain were observed in 3' non-coding regions of GHR gene. In the Danish strain, the AB genotype polymorphism of the GHR gene with its very low frequency (5%) has no effect on the production trait. While, RFLP-Dde1 showed no polymorphism with genetic variation in the location of GHR. Moreover, comparing the condition factors (K) of three different rainbow trout strains showed a significant correlation between the French (1.312 ± 0.13), Iranian (1.245 ± 0.17) and Danish strains (0.763 ± 0.1), respectively (p<0.05). In particular, the French strain obtained a higher K compared to the two others. The length-weight relationship is shown by the following equations W= 0.013 × L 2.921 , W= 0.012 ×L 3.023 and W= 0.007 × L 3.176 for French, Iranian and Danish strains, respectively. With the mean (b= 2.921), the studied French strain exhibited a negative allometric growth b<3 while the Iranian (b=3.023) and the Danish (b=3.176) showed positive allometric growths. Regardless of the underlying mechanism(s) responsible for the different relationships, the results of this study suggested that the AA and AB genotypes polymorphism of the GHR gene are not associated with condition factor and environmental variables can influence condition factor and length-weight relationship of rainbow trout strains in this study.

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Isolation, characterization, and distribution of two cDNAs encoding for growth hormone receptor in rainbow trout (Oncorhynchus mykiss)

Cited by 86 publications

References 23 publications

Characterization of GHRs, IGFs and MSTNs, and analysis of their expression relationships in blunt snout bream, Megalobrama amblycephala

Characterization of GHRs, IGFs and MSTNs, and analysis of their expression relationships in blunt snout bream, Megalobrama amblycephala

Evolution of Receptors for Growth Hormone and Somatolactin in Fish and Land Vertebrates: Lessons from the Lungfish and Sturgeon Orthologues

Growth Parameters Evaluation and Identification of Growth Hormone Receptor Gene Polymorphisms in Various Strains of Rainbow Trout Oncorhynchus mykiss

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