Isolation of a mesogenic newcastle disease virus from an acute disease in Indonesian ducks

Abstract

An outbreak with mortality and acute nervous signs in ducks is reported. A haemagglutinating virus was recovered from dead and sick ducks that was neutralised by Newcastle disease antiserum. The virus was a thermostable paramyxovirus that was classified as a mesogenic Newcastle disease virus. The virus induced the infection in young ducklings following intramuscular inoculation.

Experimental infection of duck origin virulent Newcastle disease virus strain in ducks

“…There is still debate over whether NDV can cause the disease in ducks [30,31], though many natural outbreaks were associated with NDV [10,11,14,16-19,21,23-25], and ducks had developed the disease or died after experimental infections with virulent strains at large doses [23,24,29]. Combining the results from this and other studies on ducks, some of the inconsistencies may be due to differences in NDV strain, dose and route of inoculation, breed, age, and maternal antibody level in different experiments.…”

“…Many NDV strains of different virulences have been isolated from diseased and clinically healthy ducks [10-25]. Some isolates were pathogenic for ducks, and natural ND cases in ducks have been gradually increasing in recent years [10,11,14,16-19,21,23-25], indicating that ducks may be not just reservoirs and carriers of NDV but also susceptible to infection with the disease.…”

Gambaran Patologi Anatomi dan Histopatologi Organ Pertahanan Itik Bali Pascainfeksi Buatan Avian orthoavulavirus 1 Isolat Tabanan-1/ARP/2017

“…Meskipun sering bersifat subklinis, serangan virus ND ternyata pernah dilaporkan dapat mematikan itik yang berumur muda dan menimbulkan beberapa perubahan patologi yang menyertainya (Kingston et al, 1978;Roy et al, 2000). Beberapa hasil penelitian menunjukkan bahwa sistem kekebalan spesifik (humoral dan seluler) tidak dapat berfungsi secara optimal pada ayam, itik, dan angsa yang terinfeksi virus ND karena jaringan limfoid tidak berkembang sehingga menyebabkan kelainan patologi atau kerusakan pada organ limfoid seperti timus, bursa Fabricius, dan limpa unggas (Lu et al, 2014;Anis et al, 2012;Bharathi et al, 2018;Elbestawy et al, 2019).…”

“…Pada penelitian ini, tanda klinis yang terlihat pada itik terinfeksi tidak jauh berbeda dengan yang dilaporkan oleh Kingston et al (1978), Dai et al (2014), dan Bharathi et al (2018). Tanda klinis tersebut berawal dari diare putih kehijauan, penurunan nafsu makan (anoreksia), kelesuan, terhambatnya pertumbuhan, dan bulu kusam.…”

Caractéristiques cliniques et anatomopathologiques de l’infection causée par le virus de la maladie de Newcastle; directives pour la visite des élevages et le diagnostic différentiel

“…La maladie naturelle de canards domestiques n'est qu'exceptionnellement rapportée et s'accompagne de mortalité et de signes nerveux aigus (Kingston et al 1978). Chez les Anatidés sauvages, l'infection naturelle conduisant à une maladie clinique n'a été que rarement citée.…”