2023
DOI: 10.1002/cpz1.840
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Isolation of Adult Mouse Cardiac Fibroblasts

Abir Almazloum,
Hadi Khalil

Abstract: Fibroblasts are dynamic cells of mesenchymal origin that regulate tissue homeostasis, extracellular matrix production, and acute wound healing. Fibroblasts respond to tissue injury and inflammation by differentiating into myofibroblasts and secreting extracellular matrix proteins. Fibroblasts are the principal mediators of the fibrotic response in all tissues and organs. Adult primary fibroblasts represent an essential tool for in vitro studies. Although they lack surface markers, fibroblasts are relatively ea… Show more

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Cited by 4 publications
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