1996
DOI: 10.1016/s0944-7113(96)80076-6
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Isolation of an angiotensin converting enzyme (ACE) inhibitor from Olea europaea and Olea lancea

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Cited by 115 publications
(67 citation statements)
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“…This demonstrates the great economic and social importance of this crop and the possible benefits to be derived from utilisation of any of its byproducts [1,2]. Olea europaea L. is widely studied for its alimentary use (the fruits and the oil are important components in the daily diet of a large part of the world's population), whereas the leaves are important for their secondary metabolites such as the secoiridoid compounds oleacein and oleuropein, the former responsible for hypotensive activity [3] and the latter also for hypoglycemic activity [4]. Several reports have shown that olive leaf extract has the capacity to lower blood pressure in animals [5] and increase blood flow in the coronary arteries [6], relieve arrhythmia and prevent intestinal muscle spasms [7].…”
Section: Introductionmentioning
confidence: 99%
“…This demonstrates the great economic and social importance of this crop and the possible benefits to be derived from utilisation of any of its byproducts [1,2]. Olea europaea L. is widely studied for its alimentary use (the fruits and the oil are important components in the daily diet of a large part of the world's population), whereas the leaves are important for their secondary metabolites such as the secoiridoid compounds oleacein and oleuropein, the former responsible for hypotensive activity [3] and the latter also for hypoglycemic activity [4]. Several reports have shown that olive leaf extract has the capacity to lower blood pressure in animals [5] and increase blood flow in the coronary arteries [6], relieve arrhythmia and prevent intestinal muscle spasms [7].…”
Section: Introductionmentioning
confidence: 99%
“…A number of screening studies on plants (Anderson and Anderson, 1997;Nyman et al, 1998;Duncan et al, 1999;Oh et al, 2002) and a natural class of compounds such as alkaloids (Oh et al, 2003), xanthones (Chen and Lin, 1992), terpenoids (Morigiwa et al, 1986;Hansen et al, 1996), fatty acids (Morota et al, 1987), peptides , hydrolysable tannins (Ueno et al, 1988), proanthocyanidins , flavonoids (Kameda et al, 1987;Actis-Goretta et al, 2003;Oh et al, 2004) have been reported to exert ACE inhibition activity.…”
mentioning
confidence: 99%
“…Alkaloids were absent in all the twigs extract while carotenoids were absent in all leaves extracts, this was the main difference in the phytochemical profile of the twigs and leaves. Other researches have shown that quinolone group of alkaloids, cinchonine and cinchonidine were found to be present in the plant leaves of O. europea (Hansen et al, 2006) while studies on stems showed presence of tannins, alkaloids and flavones (Geissmann et al, 2005).…”
Section: Resultsmentioning
confidence: 97%