Isolation of Citronellal from Cymbopogon nardus (L) Rendle and its Activity Test as a Burn Healing in Mice

Abstract

Citronellal is one of the main compounds of essential oils of Cymbopogon nardus (L) Rendle, which is the most important chemical compound in the cosmetic and pharmaceutical industries. This study aimed to isolate the citronellal from the essential oil of C. nardus and to study its activity as burn healing in male white mice (Mus musculus (L). The isolation method used column chromatography and a mixture of n-hexane-ethyl acetate as the mobile phase (20:1, v/v). The isolate obtained was used for in vivo assay to heal burn wound on the back of male white mice. The ointment formula 0.25%, 0.5% and 1% were prepared using vaseline flavum. Based on the spectroscopic data (UV-Vis, FTIR, and GC-MS), citronellal was successfully purified from the essential oil. In vivo test of citronellal showed that an ointment formula containing 1% of citronellal possessed good activity on burn healing.

Preparation of Modified Starch Nanoparticles from Beneng Taro (<i>Xanthosoma undipes K. Koch</i>) as Active Packaging Materials via Nanoprecipitation Method

“…4, the intensities at the top of the peak shoulder around 293 nm wavelength was originated from lemongrass oil. [21] This result shows that the modification of starch nanoparticles via nanoprecipitation method has been obtained.…”

Cytoprotective Properties of Citronella Oil (Cymbopogon nardus (L.) Rendl.) and Lemongrass Oil (Cymbopogon citratus (DC.) Stapf) through Attenuation of Senescent-Induced Chemotherapeutic Agent Doxorubicin on Vero and NIH-3T3 Cells

“…Citral was found to be the highest compound found in both oils, with different percentages for CO (15.61%) and LO (42.42%). It is confirmed from the common evidence that citral is a marker of LO (Sharma et al, 2021), while a marker of CO is citronellal (Anwar et al, 2020) which is the second most abundant compound after citral with 14.92%. These two markers are responsible for the different scents of CO and LO.…”

The Effectiveness of Various Essential Oils on the Market as Aedes Aegypti Mosquito Repellent

“…In addition, its antioxidant properties contribute to the accelerated regeneration of skin cells, making it a viable option as a remedy for burns. Until now, citronellal compounds have been isolated and used for its antibacterial properties, establishing citronella oil as one of the alternatives for medicines and household essentials (23)(24). An active ingredient called Diethiltoluamide (DEET) is still found in some repellent products available in the market.…”