Isolation of Quaternary Alkaloids fromThalictrum minusvar.minus.

Abstract

Pharmaceutical Biology Downloaded from informahealthcare.com by York University Libraries on 12/27/14 For personal use only. hima University, 24, 1. alkaloids. Recent Devlop. Chem. Carbon Compounds. 195-3 17. Pharmaceutical Biology Downloaded from informahealthcare.com by York University Libraries on 12/27/14 For personal use only.

Thalivarmine and Thalsivasine: Two New Bisbenzylisoquinoline Alkaloids fromThalictrum minusvar.minus

“…There was isolated a product, which was namend ariensin, and for which the structure (2R, 3R)-2,3-bis-(3 ,4-methylenedioxybenzyl)-1 ,4butanediol diacetate (1) was suggested on the basis of spectroscopic data (2). As such, it can be regarded as a member of the diarylbutane sub-class of natural hgnans (3), a natural product group with an increasingly significant variety of biological activity (4). We report here a short synthesis of (±)-ariensin, which supports the proposed structure of the natural product.…”

“…minus L. growing in Turkey. So far, the only alkaloids reported to occur in this variety of Iranian origin are berberine and magnoflorine (4,5).…”