Isolation of two cycloartane-type saponins from radix astragali membranacei

Abstract

In this research, two cycloartane-type saponins, including 3β-O-(2′-O-β-Dglucopyranosyl-β-D-xylopyranosyl)-6α,16β,25-trihydroxy-(20R,24S-epoxy) cycloartane and 3β-O-(2′-O-acetyl-β-D-xylopyranosyl)-6α-O-β-Dglucopyranosyl-16β,25-dihydroxy-(20R,24S-epoxy)cycloartane were isolated from polar soluble fraction of the radix astragali membranacei. Their chemical structures were determined by analyzing ESI-MS and NMR spectra. These compounds were reported as the main constituents of Astragalus membranaceus and used as the references to evaluate quality of this oriental medicine.