Isolierung, synthese und strukturbeweis von 5, 7-dihydroxy-3, 4′, 6, 8-tetramethoxy-flavon, einem neuen flavon aus ambrosia grayi nelson

Three New Flavonoids from Aerial Parts of Ambrosia Maritima L

“…A. maritima L. has been used in folkloric medicine as an antidiabetic agent [5], as well as for the treatment of bilharzia, rheumatic pain and kidney stones [2,3]. Previous phytochemical investigations of Ambrosia species resulted in the isolation of isoquercitrin, isorhamnetin and patuletin from A. artemisifolia [6,7], hispidulin from A. hispida [8], and mono-, di-, tri-and tetra-methylated flavones from other species of Ambrosia [9][10][11][12]. Due to the scarcity of literature information about the chemical constituents of A. maritima, we investigated its aerial parts and isolated three new flavonoids (1-3) together with six known methylated flavones (7,4'-dimethoxyluteolin, 6-methoxyluteolin, 7-methoxyluteolin, hispidulin, rhamnetin-3-O-β-Dglucopyranoside and tamarixetin 7-O-β-Dglucopyranoside) were isolated.…”