Isonitrile Trapping Reactions under Thermolysis of Alkoxyamines for the Synthesis of Quinolines.

Janza, Birgit; Studer, Armido

doi:10.1002/chin.200636146

Cited by 1 publication

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“…The reaction was highly amenable to alkyl 22 e , cyclopropyl 22 f , electron‐rich (4−CH 3 , 4−OCH 3 ) as well as electron‐poor (4−CF 3 , 4−NO 2 ) arylsulfonamides, anilines, benzamide, morpholine and piperidine as electron‐rich exogenous external amine source. Slight catalyst poisoning and amino‐chlorination [105] (side product) formation was observed in case of piperidine, which was greatly minimised by addition of diethylsalicylamide [106–107] (40 mol %). Low temperature (<85 °C) and molecular sieves presence was critical to drive this intra/inter‐molecular diamination efficiently and broadly because Cbz or sulphonyl protected hydroxylamine substrates were decomposed at higher temperature.…”

Section: Introductionmentioning

confidence: 99%

Transition‐Metal‐Catalyzed 1,2‐Diaminations of Olefins: Synthetic Methodologies and Mechanistic Studies

Kumar

2023

Chemistry An Asian Journal

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1,2‐Diamines are synthetically important motifs in organo‐catalysis, natural products, and drug research. Continuous utilization of transition‐metal based catalyst in direct 1,2‐diamination of olefines, in contrast to metal‐free transformations, with numerous impressive advances made in recent years (2015‐2023). This review summarized contemporary research on the transition‐metal catalyzed/mediated [e.g., Cu(II), Pd(II), Fe(II), Rh(III), Ir(III), and Co(II)] 1,2‐diamination (asymmetric and non‐asymmetric) especially emphasizing the recent synthetic methodologies and mechanistic understandings. Moreover, up‐to‐date discussion on (i) paramount role of oxidant and catalyst (ii) key achievements (iii) generality and uniqueness, (iv) synthetic limitations or future challenges, and (v) future opportunities are summarized related to this potential area.

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Section: Introductionmentioning

confidence: 99%

Transition‐Metal‐Catalyzed 1,2‐Diaminations of Olefins: Synthetic Methodologies and Mechanistic Studies

Kumar

2023

Chemistry An Asian Journal

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Isonitrile Trapping Reactions under Thermolysis of Alkoxyamines for the Synthesis of Quinolines.

Abstract: ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

Cited by 1 publication

References 6 publications

Transition‐Metal‐Catalyzed 1,2‐Diaminations of Olefins: Synthetic Methodologies and Mechanistic Studies

Transition‐Metal‐Catalyzed 1,2‐Diaminations of Olefins: Synthetic Methodologies and Mechanistic Studies

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