1998
DOI: 10.1098/rspa.1998.0291
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Isoperimetric conjugate points with application to the stability of DNA minicircles

Abstract: A conjugate point test determining an index of the constrained second variation in one-dimensional isoperimetric calculus of variations problems is described. The test is then implemented numerically to determine stability properties of equilibria within a continuum mechanics model of DNA minicircles.

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Cited by 61 publications
(52 citation statements)
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“…3. Furthermore, one of the necessary conditions for optimality is identical to the Riccati equation (17) associated with the condition L1 discussed in Sect. 3.1.…”
Section: Optimal Control Formulationmentioning
confidence: 99%
“…3. Furthermore, one of the necessary conditions for optimality is identical to the Riccati equation (17) associated with the condition L1 discussed in Sect. 3.1.…”
Section: Optimal Control Formulationmentioning
confidence: 99%
“…Further, the arguments in [19], involving a proof of the monotonicity of the eigenvalues of QSQ as a function of σ, demonstrate the analogue to Jacobi's strengthened condition: the lack of an isoperimetric conjugate point implies the existence of a local minimum. In addition, similar to Morse's theory in the unconstrained case, the number of isoperimetric conjugate points equals the maximal dimension of a subspace of H cons d on which the second variation is negative.…”
Section: Constrained Conjugate Pointsmentioning
confidence: 99%
“…In addition, we compute sheets of buckled solutions using a family of one-dimensional branches generated by the parameter continuation package AUTO [5,6]. We determine the index of configurations on these sheets via a numerical implementation of the conjugate point test developed in [19] since a closed-form solution of the differential equations is not feasible in this case.…”
Section: An Elastic Strut Clamped At Each End With a Relative Twismentioning
confidence: 99%
See 1 more Smart Citation
“…It has been applied to model the configuration and the stability of super-helically constrained DNA [31][32][33][34][35][36]. Because of the special slender and superdeformation characteristics of the elastic rod model, its equation of motion is strongly nonlinear, which makes its solution difficult to be found.…”
Section: Introductionmentioning
confidence: 99%