To understand H À /D À negative ion formation mechanism, isotope effects of plasma production and H À /D À production in volume negative ion sources are studied. Axial distributions of H À and D À densities in the source are measured directly by laser photodetachment method. In particular, experimental results concerning dependence of H À /D À density distributions on plasma parameters are presented and discussed. Isotope effect of plasma production in H 2 and D 2 discharge is observed. H À and D À densities have different spatial distributions, respectively, corresponding to those different plasma parameter conditions. D