Isquemia miocárdica aguda y trombosis ventricular asociadas a feocromocitoma

Yebra, M; Asenjo, Roberto Martín; Arrue, I.; Yepes, Manuel Paz; Valiente, María T. Bastante; Prieto, Santiago

doi:10.1157/13074851

Cited by 13 publications

(5 citation statements)

References 9 publications

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“…As with other case reports, we aim to remind clinicians of the possibility for VIP hormone production by pheochromocytomas 5–11 and the pro-thrombotic state in patients with pheochomocytoma. 1,12–18 As with our case, octreotide infusion may be helpful in managing the secretory diarrhea associated with VIP hormone production, and anticoagulation should be initiated early on to avoid cardioembolic events. With prompt vigilant management, morbidity and mortality may be significantly reduced.…”

Section: Discussionmentioning

confidence: 63%

“…5–11 Similarly, thrombosis occurring in patients with pheochromocytoma has been reported previously in only a few cases. 1,12–18 We have reviewed the existing literature on these rare presentations and include two tables with recent notable cases here for reference (see Tables 1 and 2).…”

Section: Discussionmentioning

confidence: 99%

“…21 Cardiac thrombosis associated with pheochromocytoma has only been reported in a handful of cases. 1,12–18 (see Table 2). In one case, a patient with medullary thyroid cancer and adrenal pheochromocytoma developed an intracardiac thrombus and, similar to our patient, there was no evidence of ventricular wall contraction abnormalities.…”

Section: Discussionmentioning

confidence: 99%

“…5–11 Moreover, thrombotic events have been reported rarely in patients with pheochromocytoma. 1,12–18 with intracardiac thrombus even rarer. A case of a patient with pheochromocytoma producing VIP and left ventricular thrombus in the absence of cardiomyopathy or wall motion abnormalities on echocardiogram is presented along with a review of the relevant literature.…”

Section: Introductionmentioning

confidence: 99%

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Vasoactive intestinal peptide producing pheochromocytoma and intracardiac thrombosis

et al. 2021

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A case of pheochromocytoma producing vasoactive intestinal peptide (VIP) and left ventricular thrombus in the absence of cardiomyopathy or wall motion abnormalities on echocardiogram is presented along with a review of the relevant literature. A 30-year-old female of Afghani descent with past medical history of panic attacks presented with fever, cough, sore throat, vomiting, and was found to have an 11 cm adrenal mass consistent with primary adrenocortical adenoma versus carcinoma. Her tumor elicited catechols and vasoactive intestinal peptide. Her hospitalization was complicated by left ventricular thrombosis leading to an embolic injury to her right kidney, respiratory failure, need for transient dialysis and urinary tract infections. She developed a profuse secretory diarrhea and decision was made to treat with empiric octreotide infusion and imodium with improvement in symptoms. She underwent coil and particle embolization followed by resection. Followup PET gallium scan showed no evidence of residual disease or metastasis. VIP producing pheochromocytoma associated with intracardiac thrombosis is rare. Outcomes depend on prompt diagnosis of the pheochromocytoma and multidisciplinary approach to management.

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Section: Discussionmentioning

confidence: 63%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Vasoactive intestinal peptide producing pheochromocytoma and intracardiac thrombosis

et al. 2021

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“…Mural thrombosis and systemic circulation embolism are common in patients with pheochromocytoma and catecholamine cardiomyopathy, 4 – 6 but reports of recurrent cases are relatively rare. Our report may be a helpful addition to the body of literature on pheochromocytoma recurrence with ventricular thrombus.…”

Section: Discussionmentioning

confidence: 99%

Recurrent pheochromocytoma with catecholamine cardiomyopathy and left ventricular thrombus: a case report

et al. 2021

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Pheochromocytoma is a rare and usually benign tumor of the adrenal glands. We report a case of a 40-year-old woman with recurrent pheochromocytoma and catecholamine cardiomyopathy. She had no history of other types of tumors or connective tissue disease. She had already undergone surgery twice to remove the pheochromocytoma, which had now recurred for the second time. A thrombus in the left ventricle was also noted upon imaging examination, which dissipated after anticoagulation therapy using dabigatran, allowing the patient to opt for an elective third surgery. This paper describes the clinical outcome of using the anticoagulant dabigatran to treat left ventricular thrombosis in this rare case of recurrent pheochromocytoma, and thus further contributing to the knowledge of the clinical management of this rare and complicated disease.

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