This study aims to determine the effect of information technology on business agility, in addition to what factors influence it, what parties are involved, and why information technology is needed in a company. Business agility is an ability that companies can use to see and analyze changes to make decisions in an uncertain environment, especially during the COVID-19 pandemic and in facing the challenges of industrial revolution 4.0. The research question is how can information technology affect business agility? who plays a role? , and why IT is needed in a company, and identify the influence of IT on business agility. The method used is a systematic literature review and through a review of 401 related journals, several factors have been identified that affect business agility. From several factors found, Information Technology has been identified as one of the factors that affect business agility. The results showed that Business Agility is an important aspect for the company. Business Agility is influenced by technology involvement, the role of top management, and employees of Human Resource, operations, and Information Technology divisions. With Information Technology, companies can identify and deal with business opportunities, customers and resources more effectively. It is emphasized in this paper that in the era of the Covid pandemic, the companies that can survive are those that understand technology/Technological literacy.