We find a positive association between short selling and accruals during 1988-2009, and that asymmetry between the up-and downsides of the accrual anomaly is stronger when constraints on short arbitrage are more severe (low availability of loanable shares as proxied by institutional holdings). Short arbitrage occurs primarily among firms in the top accrual decile. Asymmetry is present only on NASDAQ. Thus, there is short arbitrage of the accrual anomaly, but short-sale constraints limit its effectiveness. (JEL G14, G11) Recently, market upheavals have renewed the perennial debate between those who view short selling as causing downward price distortion, and those who argue that short selling helps correct overpricing. 1 Short interest, the amount of short selling in a stock, provides a revealing window into the determinants of arbitrage activity and the extent to which arbitrage succeeds in eliminating mispricing. We test here whether short arbitrageurs respond to firm overvaluation, and whether they succeed in correcting it, by measuring the effect on short selling of a proxy for market misvaluation and accruals, and by testing whether constraints on short arbitrage affect the degree to which mispricing