Considering its dire effects on different sectors, the coronavirus is far more than a health problem. The pandemic has hit the global economy starting with the developed world and now spreading into emerging economies. It is a fact that developing countries are more disadvantageous in this process since not only their health conditions and health services are not so sophisticated as their developed counterparts, but also macroeconomic conditions are not strong enough to endure such a long-lasting socio-economic crisis. Those countries are poorer and it is hard for them to allocate sources to the health sector. Comparing with emerging economies, the developed world also has been suffering from the severe effects of the pandemic. Because of long-lasting lock-down and contractions in the global economy, all developed economies revealed negative economic growth rates for the proceeding years. The purpose of this article is not only to compare the macroeconomic effects of the coronavirus disease 2019 (COVID-19) pandemic on developed and developing countries but also to assist economy authorities, health care leaders, and their organizations in anticipating and preempting problems by providing alternative health management policies rather than reacting. Macroeconomic variables data that are released by the World Bank and IMF will be applied to make the comparisons.