Iterative deconvolution of simultaneous<sup>99m</sup>Tc and<sup>201</sup>Tl projection data measured on a CdZnTe-based cardiac SPECT scanner

Kacperski, Krzysztof; Erlandsson, Kjell; Ben‐Haim, Simona; Hutton, Brian F.

doi:10.1088/0031-9155/56/5/012

Cited by 53 publications

(57 citation statements)

References 22 publications

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“…This effect and the pixelated design of dedicated cardiac cameras need to be considered when in-patient scatter and cross-contamination between the photopeaks is to be corrected for. Kacperski et al (2011) has proposed and validated a model-based correction algorithm for dual radionuclide imaging using 99m Tc and 201 Tl for the D-SPECT dedicated cardiac camera with pixelated CdZnTe-detectors. The method employs multiple energy windows and model equations describing the tailing effects and scatter.…”

Section: I-fp-cit (El Fakhri Et Al 2006)mentioning

confidence: 99%

“…In this paper we modify the model-based correction algorithm proposed by Kacperski et al (2011) and apply it to the new case of dual radionuclide imaging with 99m Tc and 123 I . Monte Carlo simulations of digital chest phantoms are used in combination with experimental measurement using capillary tubes to estimate the appropriate parameters to be implemented in the algorithm.…”

Section: I-fp-cit (El Fakhri Et Al 2006)mentioning

confidence: 99%

“…The model which describes the scatter in an energy window below the photopeak energy window (S ph → lo ) can be described by equation (2) (Kacperski et al 2011) …”

Section: Modelling Of Scattermentioning

confidence: 99%

“…This approach is described in section 2.4.1. Note that in the approach presented by Kacperski et al (2011) the estimation of the scatter components was used in combination with the triple energy window scatter correction approach (Ogawa et al 1991). The approach presented here directly estimates the scatter components in each energy window.…”

Section: Equations To Be Solvedmentioning

confidence: 99%

“…The D-SPECT design consists of nine smaller detectors that are exposed to in-patient scatter from activity outside their direct field of view which this approach accounts for (Kacperski et al 2011). After the convolution step inverse rebinning is applied to obtain the original projection composition.…”

Section: Equations To Be Solvedmentioning

confidence: 99%

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Model-based correction for scatter and tailing effects in simultaneous^99mTc and¹²³I imaging for a CdZnTe cardiac SPECT camera

et al. 2015

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. (2015). Model-based correction for scatter and tailing effects in simultaneous 99mTc and 123I imaging for a CdZnTe cardiac SPECT camera. Physics in Medicine and Biology, 60 (8), 3045-3063. Model-based correction for scatter and tailing effects in simultaneous 99mTc and 123I imaging for a CdZnTe cardiac SPECT camera Abstract 2015 Institute of Physics and Engineering in Medicine. An advantage of semiconductor-based dedicated cardiac single photon emission computed tomography (SPECT) cameras when compared to conventional Anger cameras is superior energy resolution. This provides the potential for improved separation of the photopeaks in dual radionuclide imaging, such as combined use of 99m Tc and 123 I . There is, however, the added complexity of tailing effects in the detectors that must be accounted for. In this paper we present a model-based correction algorithm which extracts the useful primary counts of 99m Tc and 123 I from projection data. Equations describing the in-patient scatter and tailing effects in the detectors are iteratively solved for both radionuclides simultaneously using a maximum a posteriori probability algorithm with one-step-late evaluation. Energy window-dependent parameters for the equations describing in-patient scatter are estimated using Monte Carlo simulations. Parameters for the equations describing tailing effects are estimated using virtually scatter-free experimental measurements on a dedicated cardiac SPECT camera with CdZnTedetectors. When applied to a phantom study with both 99m Tc and 123 I, results show that the estimated spatial distribution of events from 99m Tc in the 99m Tc photopeak energy window is very similar to that measured in a single 99m Tc phantom study. The extracted images of primary events display increased cold lesion contrasts for both 99m Tc and 123 I. AbstractAn advantage of semiconductor-based dedicated cardiac single photon emission computed tomography (SPECT) cameras when compared to conventional Anger cameras is superior energy resolution. This provides the potential for improved separation of the photopeaks in dual radionuclide imaging, such as combined use of 99m Tc and 123 I . There is, however, the added complexity of tailing effects in the detectors that must be accounted for. In this paper we present a model-based correction algorithm which extracts the useful primary counts of 99m Tc and 123 I from projection data. Equations describing the in-patient scatter and tailing effects in the detectors are iteratively solved for both radionuclides simultaneously using a maximum a posteriori probability algorithm with one-step-late evaluation. Energy window-dependent parameters for the equations describing in-patient scatter are estimated using Monte Carlo simulations. Parameters for the equations describing tailing effects are estimated using virtually scatter-free experimental measurements on a dedicated cardiac SPECT camera with CdZnTe-detectors. When applied to a phantom study with both 99m Tc and 123 I, results show that the estimated spatia...

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Section: I-fp-cit (El Fakhri Et Al 2006)mentioning

confidence: 99%

Section: I-fp-cit (El Fakhri Et Al 2006)mentioning

confidence: 99%

“…The model which describes the scatter in an energy window below the photopeak energy window (S ph → lo ) can be described by equation (2) (Kacperski et al 2011) …”

Section: Modelling Of Scattermentioning

confidence: 99%

Section: Equations To Be Solvedmentioning

confidence: 99%

Section: Equations To Be Solvedmentioning

confidence: 99%

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Model-based correction for scatter and tailing effects in simultaneous^99mTc and¹²³I imaging for a CdZnTe cardiac SPECT camera

et al. 2015

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Quantitation of tumor uptake with molecular breast imaging

Bache

Kappadath

2017

Medical Physics

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Using DEW scatter- and our Volumetric GM attenuation-correction methodology yielded accurate estimates of tumor counts in MBI over various tumor sizes, shapes, depths, background uptake, and compressed breast thicknesses. Accurate tumor uptake can be converted to radiotracer uptake concentration, allowing three patient-specific metrics to be calculated for quantifying absolute uptake and relative uptake change for assessment of treatment response.

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Limites de la tomoscintigraphie myocardique (TSM)

Manrique

2013

Imagerie en Coupes Du Cœur Et Des Vaisseaux

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Iterative deconvolution of simultaneous^99mTc and²⁰¹Tl projection data measured on a CdZnTe-based cardiac SPECT scanner

Cited by 53 publications

References 22 publications

Model-based correction for scatter and tailing effects in simultaneous^99mTc and¹²³I imaging for a CdZnTe cardiac SPECT camera

Model-based correction for scatter and tailing effects in simultaneous^99mTc and¹²³I imaging for a CdZnTe cardiac SPECT camera

Quantitation of tumor uptake with molecular breast imaging

Limites de la tomoscintigraphie myocardique (TSM)

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Iterative deconvolution of simultaneous99mTc and201Tl projection data measured on a CdZnTe-based cardiac SPECT scanner

Cited by 53 publications

References 22 publications

Model-based correction for scatter and tailing effects in simultaneous99mTc and123I imaging for a CdZnTe cardiac SPECT camera

Model-based correction for scatter and tailing effects in simultaneous99mTc and123I imaging for a CdZnTe cardiac SPECT camera

Quantitation of tumor uptake with molecular breast imaging

Limites de la tomoscintigraphie myocardique (TSM)

Contact Info

Product

Resources

About

Iterative deconvolution of simultaneous^99mTc and²⁰¹Tl projection data measured on a CdZnTe-based cardiac SPECT scanner

Model-based correction for scatter and tailing effects in simultaneous^99mTc and¹²³I imaging for a CdZnTe cardiac SPECT camera

Model-based correction for scatter and tailing effects in simultaneous^99mTc and¹²³I imaging for a CdZnTe cardiac SPECT camera