Itraconazole‐induced symmetrical drug‐related intertriginous and flexural exanthema (SDRIFE): a rare occurrence

Abstract

lupus erythematosus, this finding has recently been reported across the cold-induced dermatoses as well. 1,2,5 This case highlights ice-pack dermatosis as a rare but emerging and likely under recognized condition on the spectrum of cold-induced dermatoses. Additionally, cutaneous lupus erythematosus is a significant histopathologic mimic of ice-pack dermatosis, emphasizing the importance of obtaining a detailed clinical history of cold exposure when dermatologists and dermatopathologists encounter these clinical and histopathologic features. 1,2

Rare case of itraconazole induced SDRIFE (symmetrical drug‐related intertriginous and flexural exanthema)

“…[3][4][5] Only very few cases in the literature have hitherto suggested that itraconazole may cause SDRIFE. 4,6 In their case series of twelve patients from eastern India, Hassanandani et al proposed a correlation between itraconazole and SDRIFE due to the prevalent use of the drug in light of rising incidence of dermatophytoses in the region.…”

Axillary Contact Dermatitis: An Update on Potential Allergens and Management

“…68 These allergens have all been reported to cause axillary dermatitis via SCD. 58,69,70 Foods containing balsam of Peru that may lead to SCD include citrus, chocolate, tomato, and certain alcohols. 70,71 Patients with a positive patch test to balsam of Peru may experience improvement of their dermatitis after reduction of balsam of Peru-rich foods from their diet.…”

Seltener Fall von Itraconazol‐induziertem SDRIFE (symmetrisches arzneimittelbezogenes intertriginöses und flexurales Exanthem)

“…[3][4][5] In der Literatur gibt es bisher nur wenige Fälle, die darauf hindeuten, dass Itraconazol ein SDRIFE verursachen kann. 4,6 In ihrer Zu den histologischen Merkmalen des SDRIFE gehört ein oberflächliches perivaskuläres lymphozytäres Infiltrat, manchmal mit neutrophilen Granulozyten durchsetzt. Allerdings sind diese Befunde nicht spezifisch für ein SDRIFE.…”