Ivabradine inhibits carbachol-induced contractions of isolated rat urinary bladder

Aydın, Hasan; Turğut, Hasan; Kurt, Ayşegül Neşe Çıtak; Sahan, R; Kalkan, Ömer Faruk; Eren, Hüseyin Aksel; Ayar, Ahmet

doi:10.17219/acem/71197

Cited by 7 publications

(1 citation statement)

References 24 publications

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“…The discrepancy between our study and this study might originate because of a different animal model and the mechanism of action of carbachol. It was suggested that carbachol is the most powerful parasympathetic agent with a longer duration of action [18] and this situation was seen before at another urinary bladder study [19]. In addition to this, they used just 1 µM metformin dose while we used 2, 10 and 20 mM doses.…”

Section: Discussionmentioning

confidence: 90%

Are C-reactive protein, neutrophil to lymphocyte, platelet to lymphocyte ratios, and mean platelet volume related to the severity of idiopathic carpal tunnel syndrome?

Altun¹

2022

Ann Med Res

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Aim: The aim of this study was to investigate the correlation of C-reactive protein (CRP), neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), and red cell distribution width (RDW) in patients with idiopathic carpal tunnel syndrome (CTS). Methods: One hundred patients with CTS and 60 control subjects were included in this study. Medical records and laboratory findings of the participants were analyzed retrospectively between March 2019 and February 2020. Laboratory result values obtained from the members included in the study were examined. Results: There was a correlation between CRP and the severity of CTS (p<0.01). There was also a positive correlation between CRP and symptom severity scale (p<0.01) and functional status scale (p<0.01). No statistically significant changes were observed in the measurements of blood values other than CRP in the patients. Conclusions: In this study, a relationship was found between CRP, one of the hematological parameters, and the presence or severity of CTS.

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Section: Discussionmentioning

confidence: 90%

Are C-reactive protein, neutrophil to lymphocyte, platelet to lymphocyte ratios, and mean platelet volume related to the severity of idiopathic carpal tunnel syndrome?

Altun¹

2022

Ann Med Res

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Role of hyperpolarization-activated cyclic nucleotide-gated channels in aging bladder phenotype

et al. 2022

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The funny current: Even funnier than 40 years ago. Uncanonical expression and roles of HCN/f channels all over the body

Benzoni¹,

Bertoli²,

Giannetti³

et al. 2021

Progress in Biophysics and Molecular Biology

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Ivabradine inhibits carbachol-induced contractions of isolated rat urinary bladder

Abstract: The results of this in vitro study demonstrated that ivabradine inhibits cholinergic agonistinduced bladder contractions, which means that in the future ivabradine may be used in OAB treatment.

Cited by 7 publications

References 24 publications

Are C-reactive protein, neutrophil to lymphocyte, platelet to lymphocyte ratios, and mean platelet volume related to the severity of idiopathic carpal tunnel syndrome?

Are C-reactive protein, neutrophil to lymphocyte, platelet to lymphocyte ratios, and mean platelet volume related to the severity of idiopathic carpal tunnel syndrome?

Role of hyperpolarization-activated cyclic nucleotide-gated channels in aging bladder phenotype

The funny current: Even funnier than 40 years ago. Uncanonical expression and roles of HCN/f channels all over the body

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