IVF outcome in women with entire cohort of oocytes with coarse granulation in perivitelline space

Abstract

respectively. The oocyte areas at tPNfb and tPNf were significantly smaller than those at tICSI, tPB2b, and tPB2 (P <0.05). Study 2: The multivariable logistic regression analysis showed that clinical pregnancy had significant associations with group A (area of tPNfb / tPB2b, aOR: 4.8, 95% CI: 1.07-23.08, p<0.05) and group B (area of tPNf / tPB2b, aOR: 7.3, 95% CI: 1.22-47.58, p<0.05), but not with group C (area of tPNf / tPNfb, aOR: 2.08, 95% CI: 0.30-14.1, p¼0.4549).CONCLUSIONS: A significant decrease in oocyte cytoplasmic volume was observed from sperm penetration to PN fading. In addition, there were significant associations between clinical pregnancy and the degree of cytoplasmic volume change from 2 nd PB extrusion to PN fading. These results suggest that the regulation of oocyte cytoplasmic volume during fertilization would influence oocyte competence, which may predict successful pregnancy after SET.SUPPORT: None.