Coronary bifurcation lesions present a challenging lesion subset regarding
procedural complexity and worse patient outcomes as compared to simple lesions.
Drug eluting stents (DES), as the current standard of care for percutaneous
myocardial revascularization, have tubular design and uniform diameter, and
therefore, need to be subjected to a standardized set of procedural
modifications, to optimally fit and reconstruct underlying bifurcation anatomy.
Since contemporary DES have various design platforms, with diverse mechanical
properties, we must be aware of the device’s favorable characteristics and
limitations, to ensure maximal procedural safety and success. This is especially
true for bifurcation lesion stenting, during which device integrity will often be
eventually tested by undergoing specific procedural steps, such as proximal
balloon optimization, kissing-balloon inflations, or even intentional stent
crushing. In this review we address the design characteristics of contemporary
DES, their bifurcation-specific experimental testing data, and reported clinical
results, in an attempt to provide relevant information and help in device
selection for bifurcation stenting procedures.