Multi-hop wireless network (MHWN) can be easily attacked by jammers for its shared nature and open access to the wireless medium. Jamming attack may pose a significant threat to MHWN by occupying wireless channel used by legitimate users. A number of anti-jamming countermeasures have been put forward to eliminate the impact of communication disruption caused by jamming attacks. As an important building block of anti-jamming strategies, jammer localisation attracts much attention in recent years and several algorithms have been presented. However, how to locate multiple co-existing jammers receives little attention, and the efficiency and accuracy of the existing methods are still unsatisfactory. In this study, the authors focus on the localisation of sequential opening multi-jammers and put forward the multi-jammers localisation algorithm based on time series analysis (MLTSA) algorithm. The main process of MLTSA consists of four steps: detection of jamming attack, collection of received jamming signal strength, anomaly detection and separation of nodes, the existence determination and localisation of jammers. Finally, a series of simulation experiments are conducted to evaluate the correctness and effectiveness of the proposed algorithm. Experimental results show that the localisation accuracies of MLTSA are better than those of several state-of-the-art solutions.