Janoxepin and brevicompanine B: antiplasmodial metabolites from the fungus Aspergillus janus

Mass Spectrometric Characteristics of Prenylated Indole Derivatives from Marine-Derived Penicillium sp. NH-SL

“…Inspection of the NMR data (Table S1, Supplementary Materials) showed the same signals as those of brevicompanine B reported in the literature [19], so Compound 1 was identified as brevicompanine B. Compound 2 was also obtained as a white amorphous powder.…”

Oxepinamides: Novel Liver X Receptor Agonists from Aspergillus puniceus

“…Only six have been described: these are oxepinamide A-C, [8] cinereain, [10] janoxepin, [11] and brevianamide L. [9] All of these, except brevianamide L, have the same skeleton as that of oxepinamide D (1); brevianamide L shares the framework of compounds 2-4. It has been presumed that the biosynthesis of natural products featuring oxepin moieties proceeds through a thermal 6π electrocyclic ring opening of arene oxides.…”

Diketopiperazine Alkaloids from a Deep Ocean Sediment Derived Fungus Penicillium sp.

“…Brevicompanine B was also found to be active against the malaria parasite Plasmodium falciparum 3D7. 3) We have focused our attention on new bioactive alkaloids from fungi and isolation work on a deep ocean sediment derived fungus Penicillium sp. led to the finding of five new diketopiperazine alkaloids brevicompanines D-H (3-7) and two known analogs allobrevicompanine B (1) 4) and fructigenine B (2).…”