Janus nanoparticles for contrast enhancement of T1–T2 dual mode magnetic resonance imaging

Deka, Kashmiri; Guleria, Anupam; Kumar, Deepak; Biswas, Jayeeta; Lodha, Saurabh; Kaushik, S. D.; Choudhary, Saynaz A.; Dasgupta, Suman; Deb, Pritam

doi:10.1039/c8dt04038a

Cited by 17 publications

(16 citation statements)

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“…In both cases, the interactions attending the adsorption mechanism of biopolymers on the surface of MNPs are mainly electrostatic and hydrophobic interactions, and hydrogen bonding [ 42 ]. All strategies available for the surface functionalization of MNPs lead to several magnetic bio-nanocomposites characterized by different structures, including core-shell, shell-core-shell, multicores or matrix-dispersed structures, and Janus-type hetero-structures [ 44 , 45 , 46 , 47 , 48 , 49 ] ( Figure 1 ).…”

Section: Magnetic Nanoparticles: Synthesis and Functionalizationmentioning

confidence: 99%

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Polydopamine-Coated Magnetic Iron Oxide Nanoparticles: From Design to Applications

et al. 2022

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Magnetic iron oxide nanoparticles have been extensively investigated due to their applications in various fields such as biomedicine, sensing, and environmental remediation. However, they need to be coated with a suitable material in order to make them biocompatible and to add new functionalities on their surface. This review is intended to give a comprehensive overview of recent advantages and applications of iron oxide nanoparticles coated by polydopamine film. The synthesis method of magnetic nanoparticles, their functionalization with bioinspired materials and (in particular) with polydopamine are discussed. Finally, some interesting applications of polydopamine-coated magnetic iron oxide nanoparticles will be pointed out.

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Section: Magnetic Nanoparticles: Synthesis and Functionalizationmentioning

confidence: 99%

“…Copyright 2020 John Wiley and Sons); ( E ) Polyethylene glycol (PEG) stabilized MnFe 2 O 4 @MnO Janus nanoparticles (reproduced with permission from ref. [ 48 ]. Copyright 2003 Royal Society of Chemistry); ( F ) Polymer-stabilized ferromagnetic γ-Fe 2 O 3 dumbell nanoparticles (reproduced with permission from ref.…”

Section: Figurementioning

confidence: 99%

Polydopamine-Coated Magnetic Iron Oxide Nanoparticles: From Design to Applications

et al. 2022

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“…Bioimaging, as an early diagnosis tool, plays important roles in clinical treatment, which generally includes, fluorescence imaging (FI), [68] photoacoustic imaging (PA), [188,189] computed tomography imaging, [70,190] magnetic resonance imaging, [191] and multimodal imaging. [18,192,193] In recent years, luminescent Janus Figure 21.…”

Section: Bioimagingmentioning

confidence: 99%

Shedding Light on Luminescent Janus Nanoparticles: From Synthesis to Photoluminescence and Applications

Yuan

Wang

Xiang

et al. 2022

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Luminescent Janus nanoparticles refer to a special category of Janus‐based nanomaterials that not only exhibit dual‐asymmetric surface nature but also attractive optical properties. The introduction of luminescence has endowed conventional Janus nanoparticles with many alluring light‐responsive functionalities and broadens their applications in imaging, sensing, nanomotors, photo‐based therapy, etc. The past few decades have witnessed significant achievements in this field. This review first summarizes well‐established strategies to design and prepare luminescent Janus nanoparticles and then discusses optical properties of luminescent Janus nanoparticles based on downconversion and upconversion photoluminescence mechanisms. Various emerging applications of luminescent Janus nanoparticles are also introduced. Finally, opportunities and future challenges are highlighted with respect to the development of next‐generation luminescent Janus nanoparticles with diverse applications.

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“…For instance, in a Janus configuration, MnO can play the role of T 1 contrast agent, whereas the magnetic component which boosts T 2 contrast consists of MnFe 2 O 4 . [476] Radionuclide-MR Imaging Agents: The synergistic combination of PET (with high sensitivity) and MRI (with high resolution and exquisite soft tissue contrast) has attracted tremendous interest over the last decade. Magnetic nanocomposites can be used for such purposes as dual modality PET/MRI probes.…”

Section: Magnetic Nanocomposites As Effective Agents For Multimodal I...mentioning

confidence: 99%

“…For instance, in a Janus configuration, MnO can play the role of T 1 contrast agent, whereas the magnetic component which boosts T 2 contrast consists of MnFe 2 O 4 . [ 476 ]…”

Section: Applications Of Magnetic Nanocompositesmentioning

confidence: 99%

Magnetic Nanoparticle Composites: Synergistic Effects and Applications

2021

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Composite materials are made from two or more constituent materials with distinct physical or chemical properties that, when combined, produce a material with characteristics which are at least to some degree different from its individual components. Nanocomposite materials are composed of different materials of which at least one has nanoscale dimensions. Common types of nanocomposites consist of a combination of two different elements, with a nanoparticle that is linked to, or surrounded by, another organic or inorganic material, for example in a core‐shell or heterostructure configuration. A general family of nanoparticle composites concerns the coating of a nanoscale material by a polymer, SiO2 or carbon. Other materials, such as graphene or graphene oxide (GO), are used as supports forming composites when nanoscale materials are deposited onto them. In this Review we focus on magnetic nanocomposites, describing their synthetic methods, physical properties and applications. Several types of nanocomposites are presented, according to their composition, morphology or surface functionalization. Their applications are largely due to the synergistic effects that appear thanks to the co‐existence of two different materials and to their interface, resulting in properties often better than those of their single‐phase components. Applications discussed concern magnetically separable catalysts, water treatment, diagnostics‐sensing and biomedicine.

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Janus nanoparticles for contrast enhancement of T₁–T₂ dual mode magnetic resonance imaging

Abstract: MnFe2O4@MnO Janus nanoparticles efficiently enhances contrast of both T1 and T2 based MR Images.

Cited by 17 publications

References 41 publications

Polydopamine-Coated Magnetic Iron Oxide Nanoparticles: From Design to Applications

Polydopamine-Coated Magnetic Iron Oxide Nanoparticles: From Design to Applications

Shedding Light on Luminescent Janus Nanoparticles: From Synthesis to Photoluminescence and Applications

Magnetic Nanoparticle Composites: Synergistic Effects and Applications

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