Jasmonate signaling: a conserved mechanism of hormone sensing

Katsir, Leron; Chung, Hoo Sun; Koo, Abraham J.; Howe, Gregg A.

doi:10.1016/j.pbi.2008.05.004

Cited by 318 publications

(242 citation statements)

References 63 publications

Supporting

Mentioning

235

Contrasting

Unclassified

Order By: Relevance

“…The JA signal is perceived by the F-box protein COI1, which plays a key role in JA signaling (Katsir et al, 2008a), and is required for the majority of the JA-mediated responses analyzed to date (Feys et al, 1994;Xie et al, 1998;Wasternack, 2007;Balbi and Devoto, 2008). The coi1 mutant was first identified for its insensitivity to the bacterial toxin coronatine (COR), but it also displays male sterility, altered senescence, and increased susceptibility to several necrotrophic pathogens and insect pests (reviewed in Browse, 2005;Wasternack, 2007;Balbi and Devoto, 2008).…”

Section: Introductionmentioning

confidence: 99%

“…It is approximately 1000-fold more active than JA-Ile in promoting the COI1-JAZ interaction, thus hyperactivating the JA signaling pathway, and promoting the virulence of COR-producing Pseudomonas syringae (Katsir et al, 2008b). The degradation of JAZ repressors leads to the release of repression on transcription factors, such as MYC2, which regulate JA-dependent gene expression (reviewed in Chico et al, 2008;Katsir et al, 2008a;Staswick, 2008) and diverse downstream jasmonate-dependent plant functions, including resistance to fungal pathogens (Dombrecht et al, 2007).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Fusarium oxysporum hijacks COI1‐mediated jasmonate signaling to promote disease development in Arabidopsis

Thatcher

Manners

Kazan³

2009

The Plant Journal

269

298

View full text Add to dashboard Cite

SUMMARYAlthough defense responses mediated by the plant oxylipin jasmonic acid (JA) are often necessary for resistance against pathogens with necrotrophic lifestyles, in this report we demonstrate that jasmonate signaling mediated through COI1 in Arabidopsis thaliana is responsible for susceptibility to wilt disease caused by the root-infecting fungal pathogen Fusarium oxysporum. Despite compromised JA-dependent defense responses, the JA perception mutant coronatine insensitive 1 (coi1), but not JA biosynthesis mutants, exhibited a high level of resistance to wilt disease caused by F. oxysporum. This response was independent from salicylic acid-dependent defenses, as coi1/NahG plants showed similar disease resistance to coi1 plants. Inoculation of reciprocal grafts made between coi1 and wild-type plants revealed that coi1-mediated resistance occurred primarily through the coi1 rootstock tissues. Furthermore, microscopy and quantification of fungal DNA during infection indicated that coi1-mediated resistance was not associated with reduced fungal penetration and colonization until a late stage of infection, when leaf necrosis was highly developed in wild-type plants. In contrast to wild-type leaves, coi1 leaves showed no necrosis following the application of F. oxysporum culture filtrate, and showed reduced expression of senescence-associated genes during disease development, suggesting that coi1 resistance is most likely achieved through the inhibition of F. oxysporum-incited lesion development and plant senescence. Together, our results indicate that F. oxysporum hijacks non-defensive aspects of the JA-signaling pathway to cause wilt-disease symptoms that lead to plant death in Arabidopsis.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Fusarium oxysporum hijacks COI1‐mediated jasmonate signaling to promote disease development in Arabidopsis

Thatcher

Manners

Kazan³

2009

The Plant Journal

269

298

View full text Add to dashboard Cite

show abstract

“…5 Interaction of the F-box protein COI1 and one of the JAZ proteins requires the C-terminal jas domain of JAZ. 6 This interaction is promoted by JA-Ile. Among the various stereo-isomeric forms of JA-Ile, the (+)-7-iso-JA-Ile has the highest activity.…”

mentioning

confidence: 99%

“…12 Alternatives were discussed such as (i) a repertoire of different receptor properties with individual JAZ proteins, 4,13 (ii) an unidentified COI1 substrate 14 or (iii) promotion of COI1-JAZ interaction by non-conjugated jasmonates. 6 Most of these alternatives were excluded in subsequent studies.There are, however, numerous OPDA-specific responses suggesting OPDA perception via an alternative route. This route might be a COI1-independent pathway.…”

mentioning

confidence: 99%

See 1 more Smart Citation

OPDA-Ile – a new JA-Ile-independent signal?

Wasternack

Hause

2016

Plant Signaling & Behavior

View full text Add to dashboard Cite

Expression takes place for most of the jasmonic acid (JA)-induced genes in a COI1-dependent manner via perception of its conjugate JA-Ile in the SCF COI1 -JAZ co-receptor complex. There are, however, numerous genes and processes, which are preferentially induced COI1-independently by the precursor of JA, 12-oxophytodienoic acid (OPDA). After recent identification of the Ile-conjugate of OPDA, OPDA-Ile, biological activity of this compound could be unequivocally proven in terms of gene expression. Any interference of OPDA, JA, or JAIle in OPDA-Ile-induced gene expression could be excluded by using different genetic background. The data suggest individual signaling properties of OPDA-Ile. Future studies for analysis of an SCF COI1 -JAZ co-receptorindependent route of signaling are proposed. Ten years ago, the new family of JASMONATE ZIM DOMAIN (JAZ) proteins with 12 members was occasionally identified in Arabidopsis in 3 different labs. [1][2][3] This was a breakthrough in JA research, since JAZ proteins were characterized as repressors of JA-Ile-induced gene expression. With identification of these proteins, it became clear that JA-Ile is perceived by the SCF COI1 -JAZ co-receptor complex. Components of this complex are the F-box protein called CORONATINE INSENSI-TIVE 1 (COI1), the Skp1/Cullin/complex with E3 ubiquitin ligase activity and the targets of the F-box protein, the JAZ proteins. JAZ proteins repress in the absence of JA-Ile positively acting transcription factors (TFs), such as MYC2, which bind to JA responsive elements (G-boxes) in the promoters of JAIle-regulated genes. Upon stress or developmentally regulated processes, an increase in JA-Ile level occurs leading to its binding in the SCF COI1 -JAZ co-receptor complex followed by proteasomal degradation of JAZ. Consequently, the free, positively acting MYC2 can switch on JA-Ile-responsive gene expression. 4 This basic scenario could be explained mechanistically upon crystallization of the complex, where an inositol-pentakisphosphate (IP 5 ) activates JA-Ile binding. 5 Interaction of the F-box protein COI1 and one of the JAZ proteins requires the C-terminal jas domain of JAZ. 6 This interaction is promoted by JA-Ile. Among the various stereo-isomeric forms of JA-Ile, the (+)-7-iso-JA-Ile has the highest activity. 7 JA-Ile perception via the SCF COI1 -JAZ-co-receptor complex was confirmed in the last couple of years including identification of new co-repressors and adaptors (for reviews, see refs. [8][9][10] ).There is, however, one open question due to the structural specificity in binding of the ligand JA-Ile. Among 40 different jasmonate compounds the stereoisomer (+)-7-iso-JA-Ile, carrying a ring conformation similar to coronatine, was most active. 7 Even coronatine was 10-fold more active then JA-Ile, although this bacterial toxin does not occur in plants. For the methyl ester of JA, for 12-oxo-phytodienoic acid (OPDA, the precursor of JA biosynthesis), and for OPDA-Ile (Fig. 1) no detectable promotion of JAZ3-COI1 interaction was recorded...

show abstract

Jasmonic Acid Signalling

Roberts

2016

Encyclopedia of Life Sciences

View full text Add to dashboard Cite

Jasmonic acid (JA) is an important plant hormone involved in the regulation of plant development and stress responses. A central feature of JA signalling is the repression of JA responses by the JASMONATE ZIM‐DOMAIN (JAZ) protein family. JAZ proteins function to inhibit the activity of transcription factors responsible for driving the expression of JA‐responsive target genes. This is achieved by recruitment of transcriptional repressors and chromatin remodelling proteins. Perception by a COI1‐JAZ coreceptor of the main bioactive molecule in JA signalling, jasmonoyl‐ l ‐isoleucine, results in JAZ protein degradation and release of JA responses from suppression. Specificity in JA signalling is generated by a combination of JAZ protein diversity, cell specificity of JA‐responsive transcription factors and interactions with other plant hormone signalling pathways. Key Concepts (+)‐7‐iso‐jasmonoyl‐ l ‐isoleucine (JA‐Ile) is the main biologically active compound responsible for jasmonic acid (JA) signalling in higher plants. JASMONATE ZIM‐DOMAIN (JAZ) proteins function as the central regulators of jasmonate signalling. JAZ proteins recruit transcriptional repressors to inhibit the activity of transcription factors that positively regulate JA responses. The F‐box protein COI1 functions along with JAZ proteins as a JA‐Ile coreceptor that controls JA‐dependent JAZ protein degradation. Specificity in JA signalling is conferred by context‐specific interactions between JAZ proteins and their targets, and by interactions between JA and other signalling pathways. There are two major pathways for jasmonate‐dependent plant defence responses, which are controlled by antagonistic master‐regulator transcription factors. Herbivores, pathogens and symbiotic microorganisms can manipulate jasmonate signalling for their own benefit. Interactions between JAZ and DELLA proteins mediate trade‐offs between growth and defence. Jasmonates likely function as long‐distance defence signals within, and possibly even between, plants. Other bioactive jasmonates include 12‐oxo‐phytodienoic acid (OPDA) and cis ‐jasmone.

show abstract

Jasmonate signaling: a conserved mechanism of hormone sensing

Cited by 318 publications

References 63 publications

Fusarium oxysporum hijacks COI1‐mediated jasmonate signaling to promote disease development in Arabidopsis

Fusarium oxysporum hijacks COI1‐mediated jasmonate signaling to promote disease development in Arabidopsis

OPDA-Ile – a new JA-Ile-independent signal?

Jasmonic Acid Signalling

Contact Info

Product

Resources

About