Jimson "Loco" Weed Abuse in Adolescents

Abstract

Over a three-year period, 29 adolescent patients were hospitalized because of intentional Jimson weed ingestion. Their records were reviewed for the presence of signs and symptoms of atropine/scopolamine toxicity, clinical course, treatment, and outcome. Twentytwo were male and seven were female. All had mydriasis, hallucinations, and were disoriented. Tachycardia (heart rate >95), dry mucous membranes, and flushed facies were often present. Urinary retention requiring catheterization was present in five patients. Sixty-five percent (17/26) had detectable atropine or scopolamine in their urine. The average length of hospitalization was 1.8 days. No serious complications were encountered during hospitalization and full recovery was noted in all patients. Gastric lavage and hospital admission for close monitoring and medical support are essential phases of management. Physicians who care for adolescents should be aware of this relatively new form of drug abuse and its management.

Substance use and psychotic-like experiences in young people: a systematic review and meta-analysis

“…1, the searches yielded 2223 references, of which 666 were excluded as duplicates, 1243 were excluded following review of title and abstract, and a further 259 were excluded following full text review. The remaining 55 studies met inclusion criteria (Addington et al, 2019; Albertella & Norberg, 2012; Auther et al, 2012; Barkhuizen, Taylor, Freeman, & Ronald, 2019; Bassett, Schunk, & Crouch, 1996; Bechtold, Hipwell, Lewis, Loeber, & Pardini, 2016; Besli, Ikiz, Yildirim, & Saltik, 2015; Bourque, Afzali, O'Leary-Barrett, & Conrod, 2017a; Bourque et al, 2017b; Brink et al, 2020; Colins, Vermeiren, Noom, & Broekaert, 2013; Colins et al, 2009; Cruz & Domínguez, 2011; DaBreo-Otero, 2021; Dolphin, Dooley, & Fitzgerald, 2015; Drobinin et al, 2020; Evans & Raistrick, 1987; Fonseca-Pedrero, Lucas-Molina, Pérez-Albéniz, Inchausti, & Ortuño-Sierra, 2020; Forrester, 2012; Friedman, Utada, Glickman, & Morrissey, 1987; Garland & Howard, 2010; Goulter, McMahon, & Dodge, 2019; Harley et al, 2010; Hartsell, 2021; Hides et al, 2009; Jones, Calkins, Scott, Bach, & Gur, 2017; Jones, Gage, & Heron, 2018; Konings, Henquet, Maharajh, Hutchinson, & Van Os, 2008; Lansing, Plante, Fennema-Notestine, Golshan, & Beck, 2018; Levy & Weitzman, 2019; Lindgren et al, 2010; Mackie, Castellanos-Ryan, & Conrod, 2011; Mackie et al, 2021; McGorry et al, 1995; McMahon et al, 2021; Miettunen et al, 2008; Mundy, Robertson, Robertson, & Greenblatt, 1990; Opaleye et al, 2009; Rimvall et al, 2020; Schifano, Forza, & Gallimberti, 1994; Scott et al, 2009; Shakoor et al, 2015; Shervette, Schydlower, Lampe, & Fearnow, 1979; Shrier, Harris, Kurland, & Knight, 2003; Stain et al, 2016; Stainton et al, 2021; Sunderland et al, 2021; Tekulve, Alexander, & Tormoehlen, 2014; van Gastel et al, 2012; Vaughn, 2006; Wang et al, 2022; Watts et al, 2021; Whitt, Garland, & Howard, 2012; Yilmaz Kafali et al, 2022; ...…”

Angel's Trumpet (Datura stramonium) poisoning and delirium in adolescents in Winnipeg, Manitoba: Summer 2006

“…The plant D stramonium, a member of the nightshade family (3), is known by a variety of names -Jimson weed, loco weed, Angel's Trumpet, Devil's Trumpet, Moon Flower, Witch's Thimble, Devil's Apple, Thorn Apple, Stinkweed, Mad Apple, Devil's Weed, Malpitte and Green Dragon (4,5). The most common name is Jimson weed, a shortened version of 'Jamestown weed'.…”

“…The most common name is Jimson weed, a shortened version of 'Jamestown weed'. It was named after the first recorded accidental ingestion occurred in Jamestown, Virginia (USA), in 1676 (4,5).…”