Joinpoint Regression Analysis of Trends in Multiple Sclerosis Incidence in Kuwait: 1980–2019

Akhtar, Saeed; Al-Abkal, Jarrah; Alroughani, Raed

doi:10.1159/000511205

Cited by 10 publications

(10 citation statements)

References 43 publications

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“…The average annual percent change (AAPC) and corresponding 95% confidence interval (CI) were calculated as the weighted average of the segment trends. 17 The clusters were named as hot and cold spots, which were defined as the countries with significant clusters with higher or lower rates. 19 p < 0.05 was considered statistically significant.…”

Section: Discussionmentioning

confidence: 99%

Spatial and temporal patterns of prostate cancer burden and their association with Socio‐Demographic Index in Asia, 1990–2019

et al. 2021

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Background: Prostate cancer is the second most frequently diagnosed cancer for males worldwide, but the spatial and temporal trends of prostate cancer burden remain unknown in Asia. This study aimed to investigate the changing spatial and temporal trends of incidence, prevalence, mortality, disability-adjusted life year (DALY), and mortality-to-incidence ratio (MIR) of prostate cancer, and their association with the Socio-Demographic Index (SDI) in 48 Asian countries from 1990 to 2019.Methods: Data were extracted from the Global Health Data Exchange query tool, covering 48 Asian countries from 1990 to 2019. The average annual percent change was calculated to evaluate temporal trends. Spatial autocorrelation analysis was used to obtain spatial patterns, and the association between SDI and prostate cancer burden was estimated using a spatial panel model. Results:In Asia, the age-standardized incidence and prevalence of prostate cancer increased in almost all countries, and its mortality and DALY also increased in over half of the countries. Significantly regional disparities were found in Asia, and the hot spots for incidence, prevalence, mortality, and DALY were all located in Western Asia, the hot spots of percent change also occurred in Western Asia for incidence and DALY. Furthermore, SDI had a positive association with mortality (coef = 2.51, 95% confidence interval [CI]: 2.13-2.90) and negative association with DALY (coef = −14.99, 95% CI: −20.37 to −9.60) and MIR (coef = −0.95, 95%CI: −0.99 to −0.92).Conclusions: Prostate cancer burden increased rapidly throughout Asia and substantial disparities had persisted between countries. Geographically targeted interventions are needed to reduce the prostate cancer burden throughout Asia and in specific countries.

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Section: Discussionmentioning

confidence: 99%

Spatial and temporal patterns of prostate cancer burden and their association with Socio‐Demographic Index in Asia, 1990–2019

et al. 2021

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“…We used joinpoint regression analysis to assess the variation in the trends of the rate of vaccinations, SARS-CoV-2 cases, COVID-19-related ICU admissions and COVID-19-related deaths. With this technique, we can identify the week (joinpoint) where a statistically significant abrupt change in temporal trends has occurred [ 15 ]. For vaccinations against SARS-CoV-2, the analysis identified 5 joinpoints leading to 6 periods where different trends were observed ( Table 2 ).…”

Section: Resultsmentioning

confidence: 99%

“…We used a joinpoint regression model in order assess the variation in the trends of the rates of SARS-CoV-2 cases, COVID-19-related ICU admissions and COVID-19-related deaths, as previously described [ 14 ]. Briefly, this model investigates the combinations of trends that result in a statistically significantly better fit to a data series than a single-trend line fitted by Poisson regression or time-series models [ 15 ]. The Joinpoint Regression Program (3.5.2) and SPSS 20 were used to analyze the data.…”

Section: Methodsmentioning

confidence: 99%

Analysis of SARS-CoV-2 Cases, COVID-19 Outcomes and Vaccinations, during the Different SARS-CoV-2 Variants in Greece

et al. 2023

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Since the emergence of the SARS-CoV-2 Omicron variant, many issues have arisen. We report SARS-CoV-2 vaccinations, SARS-CoV-2 cases and COVID-19 outcomes in Greece during weeks 2–26 of 2021 (Alpha variant period), weeks 27–51 of 2021 (Delta variant period) and week 51 of 2021 to week 27 of 2022 (Omicron variant period). The average weekly cases were higher during the Omicron period vs. the Delta (25,354.17 cases/week) and Alpha periods (11,238.48 cases/week). The average weekly vaccinations were lower in the Omicron period (26,283.69/week) than in the Alpha and Delta period. Joinpoint regression analysis identified that the trend of SARS-CoV-2 cases increased by 88.5% during the rise of the Omicron wave in Greece. The trend of the intensive care unit (ICU) admissions related to COVID-19 decreased by 5.0% immediately after the rise of Omicron while the trend of COVID-19-related deaths decreased by 8.1% from the 5th week of the Omicron wave until the end of the study. For vaccinations, an increasing trend of 8.3% was observed in the first half of 2021 (weeks 18–25/2021), followed by a decreasing trend in weeks 26–43/2021. For the weeks before and during the early rise of Omicron (44/2021–1/2022), we identified an increasing trend of 10.7% and for weeks 2–27/2022 we observed a decreasing trend of 18.1%. Unfortunately, we do not have available data about the vaccination status of the SARS-CoV-2 cases, ICU admissions or deaths. Our findings suggest that the Omicron variant is associated with increased transmissibility and reduced morbidity and mortality despite the previous increase in the trend of SARS-CoV-2 vaccinations.

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“…Using this procedure, it is possible to determine the number of joinpoints that are necessary to assess significant changes in incidence trends over time. This technique is used to identify the calendar year (joinpoint) in which statistically significant abrupt changes in temporal trends occurred ( 21 ). The number and locations of joinpoints and the corresponding p -values were determined by Monte Carlo permutation tests, and the model fit was tested using a Bayesian information criterion.…”

Section: Methodsmentioning

confidence: 99%

Mortality rate of mental disorder trends in China from 2002 to 2020

Zhang

et al. 2022

Front. Psychiatry

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BackgroundThe number of people with mental disorders is increasing in China, but there are few studies on the temporal trends and population distribution of mental disorder mortality.MethodsThe mortality of mental disorders were derived from the China Health Statistics Yearbook published by the National Health and Family Planning Commission. Temporal trends in mortality were examined with a joinpoint regression using annual percent change (APC) and average annual percent change (AAPC). A Poisson regression model was utilized to test the population-level risk factors associated with the death of people with mental disorders.ResultsThe mortality of mental disorders in rural Chinese residents showed a decreasing trend from 2002 to 2020 [AAPC –2.06%, 95% confidence interval (CI) –3.16 to –0.91%]. The mortality of mental disorders in urban Chinese residents declined between 2005 and 2011 (APC –13.01%, 95% CI –21.08 to –4.13%). The mortality rate of mental disorders has decreased for urban males with an APC of –2.71% (95% CI –4.52 to –0.71) from 2002 to 2020. Urban women showed an increase in mental disorder mortality from 2002 to 2005 and from 2012 to 2020 with APCs of 19.65% (95% CI 0.64–42.32%) and 6.16% (95% CI 2.22–10.33%), respectively. Age was a significant risk factor for mental disorder mortality (odds ratio 1.28, 95% CI 1.23–1.32).ConclusionThe dissemination of medical and health information, investment in medical and health resources, and the modification and optimization of regulations have led to a decrease in mental disorder mortality in China. It is vital to devote greater attention to elderly individuals suffering from mental disorders.

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Joinpoint Regression Analysis of Trends in Multiple Sclerosis Incidence in Kuwait: 1980–2019

Cited by 10 publications

References 43 publications

Spatial and temporal patterns of prostate cancer burden and their association with Socio‐Demographic Index in Asia, 1990–2019

Spatial and temporal patterns of prostate cancer burden and their association with Socio‐Demographic Index in Asia, 1990–2019

Analysis of SARS-CoV-2 Cases, COVID-19 Outcomes and Vaccinations, during the Different SARS-CoV-2 Variants in Greece

Mortality rate of mental disorder trends in China from 2002 to 2020

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