Joint association of obesity and hypertension with disability in the elderly—A community-based study of residents in Shanghai, China

Su, Peng; Ding, Haiyang; Zhang, W.; Duan, Guangfeng; Yu, Yan; Long, J. Scott; Du, Le; Xie, Chunyan; Jin, Chunlin; Hu, Chaoqun; Sun, Zhi‐Gang; Duan, Z.; Gong, Lingling

doi:10.1007/s12603-016-0777-z

Cited by 10 publications

(19 citation statements)

References 40 publications

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“…Although hypertension is one of the most important preventable contributors to disease and death [30], several studies also show different result when focusing on the relationship between hypertension and disability [11,12,31,32]. For example, Uddin et al found hypertension was signi cantly associated with lower ADL scores in Bangladesh [31]; our previous study indicated that simple hypertension wasn't signi cantly associated with ADL/IADL disability [24]. In present study, we found only poor hypertension control was associated with ADL/IADL disability, while hypertension control was not.…”

Section: Discussionmentioning

confidence: 99%

“…About 50% eligible participants from this street o ce were randomly targeted through use of a local household registry. Details of inclusion criteria, data collection and quality control procedure have been previously reported [24,25]. In brief, 9408 community-dwelling residents, who aged 60 years or older and had living in Shanghai for more than 5 years, were screened.…”

Section: Study Populationmentioning

confidence: 99%

“…The IADL scale included 8 items: ability to use telephone, shopping, food preparation, housekeeping, laundry, using transport, medical care and nancial management. The ADL or IADL disability was de ned as a disability in any of the 6 ADL items or 8 IADL items [24,28,29].…”

Section: Measurement Of Disabilitymentioning

confidence: 99%

“…However, overweight and obesity in combination with disability was associated with disproportionately high rates of hypertension only in women [23]. In our previous study, for individuals with hypertension, obesity was signi cantly associated with ADL disability, but not with IADL disability [24]. On further re ection, the control of blood pressure wasn't taken into account in those with hypertension, and this may have affected the outcome.…”

mentioning

confidence: 91%

“…As a result of population aging, advances in medical technology, improvements in lifestyle and wide spread of chronic diseases, the proportion of disability is increasing [3]. Among common chronic diseases, hypertension is the leading preventable risk factor for premature disability and death worldwide [4], approximately 24•1% in men and 20.1% in women had hypertension [5]. More remarkable, while high-income countries have begun to reduce hypertension in their populations through strong public health policies, many developing countries are seeing growing numbers of people who suffer from hypertension [6].…”

mentioning

confidence: 99%

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Interactive Effect of Hypertension and Obesity on Disability among Older People: A Observational Study

Yang

Dong³

et al. 2020

Preprint

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Background Both hypertension and obesity are strongly associated with disability, but these associations are in debate among older people. In this context, our study aimed to examine the interactive effect of hypertension and obesity with disability, especially including the control of blood pressure. Methods A cross-sectional study was conducted from August to October 2018 in Shanghai, 8648 community-dwelling individuals with a mean age of 70.39 years. Obesity was measured using the body mass index (BMI) in World Health Organization (WHO) Asia criteria. Hypertension control was defined as treatment with antihypertensive medication and a measured blood pressure of less than 140/90 mm Hg. Disability was measured using the self-reported physical self-maintenance scale (PSMS) and the instrumental activities of daily living (IADL) scale developed by Lawton and Brody. Logistic regression with 95% confidence intervals (CI) was used to explore the interactive effect of hypertension and obesity on disability. Results A total of 33.60% of participants reported hypertension control, 6.54% for poor hypertension control, 9.27% for ADL disability, and 32.47% for IADL disability. After adjusting social demographics and chronic conditions, versus without hypertension: in independent analyses, poor hypertension control was a risk factor (OR for ADL disability = 1.47, 95% CI = 1.10–1.96; OR for IADL disability = 1.55, 95% CI = 1.27–1.91); in interactive analyses, poor hypertension control was a risk factor in obese subset (OR for ADL disability = 1.73, 95% CI = 1.09–2.74; OR for IADL disability = 1.80, 95% CI = 1.31–2.47), but a protective factor in underweight subset (OR for ADL disability = 0.33, 95% CI = 0.18–0.62; OR for IADL disability = 0.32, 95% CI = 0.20–0.51). Conclusions Poor hypertension control, independent of its consequences, is a risk factor for disability among older people. In addition, hypertension and BMI status have interactive effect on disability among older people. Poor hypertension control is a risk factor among obese individuals, but a protective factor among underweight individuals.

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Section: Discussionmentioning

confidence: 99%

Section: Study Populationmentioning

confidence: 99%

Section: Measurement Of Disabilitymentioning

confidence: 99%

mentioning

confidence: 91%

mentioning

confidence: 99%

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Interactive Effect of Hypertension and Obesity on Disability among Older People: A Observational Study

Yang

Dong³

et al. 2020

Preprint

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Muscle‐to‐fat ratio identifies functional impairments and cardiometabolic risk and predicts outcomes: biomarkers of sarcopenic obesity

Hsu

Lee

et al. 2021

J cachexia sarcopenia muscle

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Background Sarcopenic obesity aims to capture the risk of functional decline and cardiometabolic diseases, but its operational definition and associated clinical outcomes remain unclear. Using data from the Longitudinal Aging Study of Taipei, this study explored the roles of the muscle-to-fat ratio (MFR) with different definitions and its associations with clinical characteristics, functional performance, cardiometabolic risk and outcomes. Methods (1) Appendicular muscle mass divided by total body fat mass (aMFR), (2) total body muscle mass divided by total body fat mass (tMFR) and (3) relative appendicular skeletal muscle mass (RASM) were measured. Each measurement was categorized by the sex-specific lowest quintiles for all study participants. Clinical outcomes included all-cause mortality and fracture. Results Data from 1060 community-dwelling older adults (mean age: 71.0 ± 4.8 years) were retrieved for the study. Overall, 196 (34.2% male participants) participants had low RASM, but none was sarcopenic. Compared with those with high aMFR, participants with low aMFR were older (72 ± 5.6 vs. 70.7 ± 4.6 years, P = 0.005); used more medications (2.9 ± 3.3 vs. 2.1 ± 2.5, P = 0.002); had a higher body fat percentage (38 ± 4.8% vs. 28 ± 6.4%, P < 0.001),

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BMI, weight change, and incidence of disability among Korean adults: A nationwide retrospective cohort study

Choi

Kim

Han

2021

Disability and Health Journal

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Joint association of obesity and hypertension with disability in the elderly—A community-based study of residents in Shanghai, China

Cited by 10 publications

References 40 publications

Interactive Effect of Hypertension and Obesity on Disability among Older People: A Observational Study

Interactive Effect of Hypertension and Obesity on Disability among Older People: A Observational Study

Muscle‐to‐fat ratio identifies functional impairments and cardiometabolic risk and predicts outcomes: biomarkers of sarcopenic obesity

BMI, weight change, and incidence of disability among Korean adults: A nationwide retrospective cohort study

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