Joint China-US Call for Employing a Transdisciplinary Approach to Emerging Infectious Diseases

Mazet, Jonna A. K.; Qin, Wei; Zhao, Guoping; Cummings, Derek A. T.; Desmond, James; Rosenthal, Joshua J. C.; King, Charles H.; Cao, Wu‐Chun; Chmura, Aleksei A.; Hagan, Emily; Zhang, Shuyi; Xiao, Xiangming; Xu, Jianguo; Z, Shi; Feng, Feng; Liu, Xiuping; Pan, Weiqing; Zhu, Guang; Zuo, Liyao; Daszak, Peter

doi:10.1007/s10393-015-1060-1

Cited by 4 publications

(5 citation statements)

References 19 publications

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“…Similarly, a previous global pandemic caused by SARS coronavirus in 2002 resulted in over 800 human deaths with an economic impact of US$50 billion. The World Bank estimated economic losses from fatal zoonoses between 1997 and 2009 at US$80 billion and appraises that US$6.7 billion per year could be saved globally by preventing emerging disease outbreaks (Mazet et al , ).…”

Section: Discussionmentioning

confidence: 99%

Bat‐borne viruses in Africa: a critical review

et al. 2020

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In Africa, bat-borne zoonoses emerged in the past few decades resulting in large outbreaks or just sporadic spillovers. In addition, hundreds of more viruses are described without any information on zoonotic potential. We discuss important characteristics of bats including bat biology, evolution, distribution and ecology that not only make them unique among most mammals but also contribute to their potential as viral reservoirs. The detection of a virus in bats does not imply that spillover will occur and several biological, ecological and anthropogenic factors play a role in such an event. We summarize and critically analyse the current knowledge on African bats as reservoirs for corona-, filo-, paramyxo-and lyssaviruses. We highlight that important information on epidemiology, bat biology and ecology is often not available to make informed decisions on zoonotic spillover potential. Even if knowledge gaps exist, it is still important to recognize the role of bats in zoonotic disease outbreaks and implement mitigation strategies to prevent exposure to infectious agents including working safely with bats. Equally important is the crucial role of bats in various ecosystem services. This necessitates a multidisciplinary One Health approach to close knowledge gaps and ensure the development of responsible mitigation strategies to not only minimize risk of infection but also ensure conservation of the species.

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Section: Discussionmentioning

confidence: 99%

Bat‐borne viruses in Africa: a critical review

et al. 2020

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“… 1 The majority of human pathogens are of animal origin and especially have wild animals as host reservoirs. 2 , 3 Studying the microbiome of wild animals will provide valuable information to deliver an advance alert of or prevent putative infection outbreaks. Vultures are nature's most successful scavengers, feeding on the carcasses of dead animals without suffering any apparent illness effect.…”

Section: Introductionmentioning

confidence: 99%

Metataxonomics reveal vultures as a reservoir for Clostridium perfringens

Xiao

Yang

et al. 2017

Emerging Microbes & Infections

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The Old World vulture may carry and spread pathogens for emerging infections since they feed on the carcasses of dead animals and participate in the sky burials of humans, some of whom have died from communicable diseases. Therefore, we studied the precise fecal microbiome of the Old World vulture with metataxonomics, integrating the high-throughput sequencing of almost full-length small subunit ribosomal RNA (16S rRNA) gene amplicons in tandem with the operational phylogenetic unit (OPU) analysis strategy. Nine vultures of three species were sampled using rectal swabs on the Qinghai-Tibet Plateau, China. Using the Pacific Biosciences sequencing platform, we obtained 54 135 high-quality reads of 16S rRNA amplicons with an average of 1442±6.9 bp in length and 6015±1058 reads per vulture. Those sequences were classified into 314 OPUs, including 102 known species, 50 yet to be described species and 161 unknown new lineages of uncultured representatives. Forty-five species have been reported to be responsible for human outbreaks or infections, and 23 yet to be described species belong to genera that include pathogenic species. Only six species were common to all vultures. Clostridium perfringens was the most abundant and present in all vultures, accounting for 30.8% of the total reads. Therefore, using the new technology, we found that vultures are an important reservoir for C. perfringens as evidenced by the isolation of 107 strains encoding for virulence genes, representing 45 sequence types. Our study suggests that the soil-related C. perfringens and other pathogens could have a reservoir in vultures and other animals.

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“…In absence of safe vaccine or effective antiviral Zika medication for prevention and control Zika virus infection, early laboratorial diagnosis includes nucleic acid detection, serological test, and isolation of virus and epidemiology and clinical risk assessment and syndromic surveillance is crucial [1,3,13]. Nevertheless, there remains a need to build a platform with function of effective surveillance, recovery, preparedness, consultation and communication, and to share surveillance based on the principle of sincerity, real time problem-solving and results-giving, and good faith towards collaborative global health solutions [4,[14][15][16].…”

Section: Leveraging On Current and Innovative China-africa Health Devmentioning

confidence: 99%

“…Fostering surveillance capacity in laboratory, clinical, veterinary and allied health sciences in the Africa continent are critical to overcoming the growing burden of diseases and ensuring a healthy future of its citizens [14,15]. Meeting the urgent growing healthcare needs in Africa requires strategic and technical approaches in the development and integration of sound and harmonized regulatory systems for diagnostic products, new drugs and vaccine R&D. While reinforcing the national and international public health laboratories networks are able to improve collaborative and participative early disease detection, early warning and surveillance research in guiding proactive vigilance and smart response activities.…”

Section: Leveraging On Current and Innovative China-africa Health Devmentioning

confidence: 99%

“…This is critical in averting or reducing the persistent malnutrition, under-nutrition and related health complications and diseases (e.g. malnutrition linked Kwashiorkor or rickets, obesity, typhoid, diarrhea, dysentery) resulted in children and youth developmental retardation, poor educational performance, poor quality of life and living including high DALY and low QALY short life expectancy, worsening the vicious cycle of poverty and premature death documented in Africa countries [4,9,11,13,14]. Similar high public health challenges and burden in Africa were recorded in China before 1980s, mainly in Chinese rural communities circumventing with the implementation of the Chinese rural cooperative medical insurance schemes.…”

Section: Mobilizing On Mitigation Of Climatic Changes and Disasters Amentioning

confidence: 99%

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The value of China-Africa health development initiatives in strengthening “One Health” strategy

Tambo

Tang

et al. 2017

Global Health Journal

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Implementing national to community-based "One Health" strategy for human, animal and environmental challenges and migrating-led consequences offer great opportunities, and its value of sustained development and wellbeing is an imperative. "One Health" strategy in policy commitment, partnership and financial investment are much needed in advocacy, contextual health human-animal and environmental development. Therefore, appropriate and evidence-based handling and management strategies in moving forward universal health coverage and sustainable development goals (SDGs) are essential components to the China-Africa health development initiatives. It is necessary to understand how to strengthen robust and sustainable "One Health" approach implementation in national and regional public health and disaster risk reduction programs. Understanding the foundation of "One Health" strategy in China-Africa public health cooperation is crucial in fostering health systems preparedness and smart response against emerging and re-emerging threats and epidemics. Building the value of China-Africa "One Health" strategy partnerships, frameworks and capacity development and implementation through leveraging on current and innovative China-Africa health initiatives, but also, mobilizing efforts on climatic changes and disasters mitigation and lifestyle adaptations strategies against emerging and current infectious diseases threats are essential to establish epidemic surveillance-response system under the concept of global collaborative coordination and lasting financing mechanisms. Further strengthen local infrastructure and workforce

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Joint China-US Call for Employing a Transdisciplinary Approach to Emerging Infectious Diseases

Cited by 4 publications

References 19 publications

Bat‐borne viruses in Africa: a critical review

Bat‐borne viruses in Africa: a critical review

Metataxonomics reveal vultures as a reservoir for Clostridium perfringens

The value of China-Africa health development initiatives in strengthening “One Health” strategy

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