Joint Injections

Provenzano, David; Chandwani, Kailash

doi:10.1016/b978-0-323-08340-9.00071-2

Cited by 4 publications

(3 citation statements)

References 149 publications

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“…However, there is no conclusive evidence that differences in viscosupplement physical properties translate into superior clinical efficacy. [ 95 ] The properties sought are mainly the molecule network, rheological properties, water homeostasis, network interactions with other macromolecules, and matrix and cell surface interactions.…”

Section: Biomaterials and Viscosupplement‐based Therapiesmentioning

confidence: 99%

Engineering of Viscosupplement Biomaterials for Treatment of Osteoarthritis: A Comprehensive Review

et al. 2022

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Osteoarthritis (OA) is a progressive degenerative disease that causes severe pain and functional limitation, especially during locomotion. It is the most common arthritis type that damages the surface of articular cartilage until the underlying bone. In the past decade, the scientific community has made a considerable effort to improve or discover therapeutical products used as a form of conservative treatment capable of restoring the damaged articular tissue, avoiding, as far as possible, the use of surgical practices. The most common and direct nonoperative application available for OA treatment is the viscosupplementation (VS) procedure that demonstrates a safe, effective method and is less painful for the patients. The most recent works dealing with the design, development, and validation of viscosupplement products in preclinical and clinical trials for OA treatment are overviewed herein. In general, despite the development of new products, hyaluronic acid continues to be among the most reported intra‐articular viscosupplement products used in clinical trials, typically used as an isolated product or conjugated with other biologicals or drugs, such as platelet‐rich plasma and corticosteroids (CS). However, this issue is still demanding innovation. Approaches comprising new biomaterials as VS products, with intrinsic bioactivity, economical, and environmental friendliness, are required.

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Section: Biomaterials and Viscosupplement‐based Therapiesmentioning

confidence: 99%

Engineering of Viscosupplement Biomaterials for Treatment of Osteoarthritis: A Comprehensive Review

et al. 2022

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“…Hip arthroplasty is one of the most efficient, cost-effective, and consistent surgical strategies, replacing the deteriorated hip joint with an artificial one . According to the anatomy, the hip joint is a ball-and-socket device that connects the thighbone to the pelvis. , It carries half of the human body weight, making it the second most crucial load-bearing structure . The femoral stem, head, and acetabular components are the three distinct parts of a hip joint. , The ball-shaped femoral head at the top of the thighbone is joined to the pelvic bone to form a cup-based structure (a socket-shaped acetabulum).…”

Section: Introductionmentioning

confidence: 99%

“…1 According to the anatomy, the hip joint is a ball-and-socket device that connects the thighbone to the pelvis. 2,3 It carries half of the human body weight, making it the second most crucial load-bearing structure. 4 The femoral stem, head, and acetabular components are the three distinct parts of a hip joint.…”

Section: Introductionmentioning

confidence: 99%

Comprehensive Review on Biomaterials and Their Inherent Behaviors for Hip Repair Applications

Sathishkumar,

Paulraj,

Chakraborti

et al. 2023

ACS Appl. Bio Mater.

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Developing biomaterials for hip prostheses is challenging and requires dedicated attention from researchers. Hip replacement is an inevitable and remarkable orthopedic therapy for enhancing the quality of patient life for those who have arthritis as well as trauma. Generally, five types of hip replacement procedures are successfully performed in the current medical market: total hip replacements, hip resurfacing, hemiarthroplasty, bipolar, and dual mobility systems. The average life span of artificial hip joints is about 15 years, and several studies have been conducted over the last 60 years to improve the performance and thereby increase the lifespan of artificial hip joints. Present-day prosthetic hip joints are linked to the wide availability of biomaterials. Metals, ceramics, and polymers are some of the most promising types of biomaterials; nevertheless, each biomaterial has advantages and disadvantages. Metals and ceramics fail in most applications owing to stress shielding and the emission of wear debris; ongoing research is being carried out to find a remedy to these unfavorable responses. Recent research found that polymers and composites based on polymers are significant alternative materials for artificial joints. With growing research and several biomaterials, recent reviews lag in effectively addressing hip implant materials' individual mechanical, tribological, and physiological behaviors. This Review comprehensively investigates the historical evolution of artificial hip replacement procedures and related biomaterials' mechanical, tribological, and biological characteristics. In addition, the most recent advances are also discussed to stimulate and guide future researchers as they seek more effective methods and synthesis of innovative biomaterials for hip arthroplasty application.

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