Joint replacement components made of hot-forged and surface-treated Ti-6Al-7Nb alloy

Semlitsch, M.; Weber, H. P.; Streicher, Robert; Schön, R.

doi:10.1016/0142-9612(92)90018-j

Cited by 197 publications

(67 citation statements)

References 3 publications

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“…The superiority of titanium comes from its mechanical, physicochemical, and biological properties, particularly immunotolerance and cytocompatibility 1,2) . However because of needs to improve its mechanical properties, titanium alloys such as Ti-6Al-4V, Ti-6Al-7Nb, have also been used for dental and orthopedic material [3][4][5] . 1) Although titanium alloys are still widely used in medicine, some concern has been expressed over its use since it appears that small amounts of both vanadium and aluminum, released in the human body, induce possible cytotoxic effect and neurological disorders, respectively [6][7][8] .…”

Section: Introductionmentioning

confidence: 99%

Biocompatibility of Ti-8Ta-3Nb alloy with fetal rat calvarial cells

Cho

Cui

Kim

et al. 2006

J Korean Acad Periodontol

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Section: Introductionmentioning

confidence: 99%

Biocompatibility of Ti-8Ta-3Nb alloy with fetal rat calvarial cells

Cho

Cui

Kim

et al. 2006

J Korean Acad Periodontol

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“…This so-called stress shielding effect is caused directly by the mismatch in the stiffness of the implant material with that of the surrounding natural bone. [18][19][20] Several solutions to this problem have been found, including more flexible designs and the use of materials with relatively low moduli.…”

Section: Introductionmentioning

confidence: 99%

Composition/Phase Structure and Properties of Titanium-Niobium Alloys

2003

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This study attempts to develop Ti-Nb alloys with elastic moduli that approach that of human bone. The experimental results reveal that the microstructure of a Ti-Nb alloy that contains 14 mass% Nb consists of and phases, with phase being the dominant one. The proportion of the phase decreases gradually as the Nb content increases, and the microstructure becomes completely the phase when the Nb content exceeds 34 mass%. Moreover, the ! phase can be detected using XRD and TEM in alloys with a Nb content from 30 to 34 mass%. Over the Nb range studied (14 to 40 mass%), the elastic modulus decreases from 14 to 26 mass% Nb, and then increases to a maximum at 34 mass% Nb, before falling again as Nb content is increased further. The elastic modulus of the Ti-Nb alloys is closely related to the microstructure (or Nb content) of the alloys. The fall in the elastic modulus with the increasing Nb content from 14 to 26 mass% is associated with a gradual decrease in the proportion of the phase in the microstructure, while the precipitation of the ! phase accounts for the increase in the elastic modulus over the intermediate range of Nb (30 to 34 mass%). The tensile strength of Ti-Nb alloys increases slightly from 14 to 26 mass% Nb, and then increases markedly with a Nb content of up to 34 mass%, before falling drastically as Nb content is increased further. A similar pattern was obtained for 0.2% proof stress, while the elongation vs. %Nb curve was just the reverse of the T.S. vs. %Nb curve, as expected. A Ti-Nb alloy with a relatively high Nb content (above 36 mass%) is preferred to other compositions for use in medical implants with a reduced stress shielding effect.

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“…It has been reported that metallic vanadium is strongly toxic to cells by Steinemann 1) and Okazaki. 2) Naturally, the development and application of vanadium-free titanium alloys to surgical implants has created great interest among researchers around the world, [3][4][5] but there are few clinical application cases. In this paper, two types of vanadium-free titanium alloys are introduced.…”

Section: Introductionmentioning

confidence: 99%

Application of Vanadium-Free Titanium Alloys to Artificial Hip Joints

et al. 2002

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The application of titanium and its alloys to surgical implants has created much interest recently. Ti-6Al-4V has been used for numerous applications that require high mechanical properties, however this alloy contains vanadium, which has been proven to be cytotoxic. Two types of vanadium-free titanium alloys were developed and applied to artificial hip joints. As for the cemented type, Ti-15Mo-5Zr-3Al alloy was adopted because of its high fatigue strength, and its low elastic modulus, which approaches bone elasticity. As for the non-cemented type, Ti-6Al-2Nb-1Ta-0.8Mo alloy was adopted because of its less decrease of fatigue strength through heat treatments up to 1270 K, which is necessary to create the porous surface to activate the reaction between the implant and the bone. In addition, new coatings and bioactive methods were applied to the newly developed non-cemented type of prostheses. These hip joints are now successfully being used with excellent clinical results.

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Joint replacement components made of hot-forged and surface-treated Ti-6Al-7Nb alloy

Cited by 197 publications

References 3 publications

Biocompatibility of Ti-8Ta-3Nb alloy with fetal rat calvarial cells

Biocompatibility of Ti-8Ta-3Nb alloy with fetal rat calvarial cells

Composition/Phase Structure and Properties of Titanium-Niobium Alloys

Application of Vanadium-Free Titanium Alloys to Artificial Hip Joints

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