Journey of begomovirus betasatellite molecules: from satellites to indispensable partners

Mubin, Muhammad; Ijaz, Siddra; Nahid, Nazia; Hassan, Muhammad Arshad Shehzad; Younus, Ayesha; Qazi, Javaria; Nawaz-ul-Rehman, Muhammad Shah

doi:10.1007/s11262-019-01716-5

Cited by 20 publications

(15 citation statements)

References 94 publications

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“…Betasatellites and deltasatellites are two groups of satellite ssDNA molecules (in addition to alphasatellitids discussed above) associated with geminivirids and classified into two separate genera within the family Tolecusatellitidae. Unlike alphasatellitids, betasatellites and deltasatellites encode neither capsid (by definition) nor replication proteins, with deltasatellites being noncoding altogether (216)(217)(218)(219).…”

Section: The Virospherementioning

confidence: 99%

Viruses Defined by the Position of the Virosphere within the Replicator Space

Koonin

Dolja

Krupovìč

et al. 2021

Microbiol Mol Biol Rev

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Section: The Virospherementioning

confidence: 99%

Viruses Defined by the Position of the Virosphere within the Replicator Space

Koonin

Dolja

Krupovìč

et al. 2021

Microbiol Mol Biol Rev

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“…DNA-B is involved in the systemic (cell to cell) and local (nucleus to cytoplasm) movements of begomovirus and involved proteins aremovement protein (MP) and nuclear shuttle protein (NSP) respectively [ 10 ]. The alphasatellites and betasatellites are predominantly associated with monopartite begomoviruses [ 15 , 16 ] and a few cases have been reported for deltasatellites [ 17 ]. The alphasatellite belongs to family Alphasatellitidae , encoding a single protein alpha-rep and includes a hairpin structure at the origin of replication [ 15 ].…”

Section: Introductionmentioning

confidence: 99%

Role of Diversity and Recombination in the Emergence of Chilli Leaf Curl Virus

et al. 2022

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Chilli leaf curl virus (ChiLCV), (Genus Begomovirus, family Geminiviridae) and associated satellites pose a serious threat to chilli production, worldwide. This study highlights the factors accountable for genetic diversity, recombination, and evolution of ChiLCV, and associated chilli leaf curl alphasatellite (ChiLCA) and chilli leaf curl betasatellite (ChiLCB). Phylogenetic analysis of complete genome (DNA-A) sequences of 132 ChiLCV isolates from five countries downloaded from NCBI database clustered into three major clades and showed high population diversity. The dN/dS ratio and Tajima D value of all viral DNA-A and associated betasatellite showed selective control on evolutionary relationships. Negative values of neutrality tests indicated purified selection and an excess of low-frequency polymorphism. Nucleotide diversity (π) for C4 and Rep genes was higher than other genes of ChiLCV with an average value of π = 18.37 × 10−2 and π = 17.52 × 10−2 respectively. A high number of mutations were detected in TrAP and Rep genes, while ChiLCB has a greater number of mutations than ChiLCA. In addition, significant recombination breakpoints were detected in all regions of ChiLCV genome, ChiLCB and, ChiLCA. Our findings indicate that ChiLCV has the potential for rapid evolution and adaptation to a range of geographic conditions and could be adopted to infect a wide range of crops, including diverse chilli cultivars.

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“…Alphasatellites, betasatellites and deltasatellites are small single-stranded (ss) circular DNA molecules associated with nanoviruses and geminiviruses [ 1 ]. Alphasatellites are capable of replicating their own genome, while betasatellites and deltasatellites are trans-replicated by a helper or cognate virus [ 2 ]. Geminialphasatellites (subfamily Geminialphasatellitinae ) are single-stranded circular molecules of ~1370–1400 nucleotides (nts) that are associated with begomoviruses and mastreviruses from the family Geminiviridae [ 3 , 4 ].…”

Section: Introductionmentioning

confidence: 99%

Patterns of Genetic Diversity among Alphasatellites Infecting Gossypium Species

et al. 2022

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Alphasatellites are small single-stranded circular DNA molecules associated with geminiviruses and nanoviruses. In this study, a meta-analysis of known alphasatellites isolated from the genus Gossypium (cotton) over the last two decades was performed. The phylogenetic and pairwise sequence identity analysis suggested that cotton-infecting begomoviruses were associated with at least 12 different alphasatellites globally. Three out of twelve alphasatellite were associated with cotton leaf curl geminiviruses but were not isolated from cotton plants. The cotton leaf curl Multan alphasatellite, which was initially isolated from cotton, has now been reported in several plant species, including monocot plants such as sugarcane. Our recombination analysis suggested that four alphasatellites, namely cotton leaf curl Lucknow alphasatellites, cotton leaf curl Multan alphasatellites, Ageratum yellow vein Indian alphasatellites and Ageratum enation alphasatellites, evolved through recombination. Additionally, high genetic variability was detected among the cotton-infecting alphasatellites at the genome level. The nucleotide substitution rate for the replication protein of alphasatellites (alpha-Rep) was estimated to be relatively high (~1.56 × 10−3). However, unlike other begomoviruses and satellites, the first codon position of alpha-Rep rapidly changed compared to the second and third codon positions. This study highlights the biodiversity and recombination of alphasatellites associated with the leaf curl diseases of cotton crops.

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Journey of begomovirus betasatellite molecules: from satellites to indispensable partners

Cited by 20 publications

References 94 publications

Viruses Defined by the Position of the Virosphere within the Replicator Space

Viruses Defined by the Position of the Virosphere within the Replicator Space

Role of Diversity and Recombination in the Emergence of Chilli Leaf Curl Virus

Patterns of Genetic Diversity among Alphasatellites Infecting Gossypium Species

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