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Abstract

SummaryTwo modifications to the conventional procedure of crosscorrelation are described, widely used for establishing the relative alignment of the members of a set of images from which a higher resolution or more interpretable restoration is sought. Both achieve a high and sharp peak in circumstances where the conventional peak is too ill defined to be recognizable: neither involves significant additional computation time. The more general method requires rough knowledge of the imaging conditions, but a variant applicable to images with axial resolution has no such requirement. In addition, a least-squares procedure is presented for achieving an optimum compromise between many pair-wise displacement measurements, preventing the accumulation of alignment errors across a set of images.

Ex vivo tissue imaging for radiology–pathology correlation: a pilot study with a small bore 7-T MRI in a rare pigmented ganglioglioma exhibiting complex MR signal characteristics associated with melanin and hemosiderin

“…To investigate if the MD value reflects cellularity, the cell number was counted by image analysis on the digitized slides. Nuclear count was used to define cellularity in a given ROI using the computer software, “Image Scope.” Previous studies indicated that paraffin processing usually causes shrinkage of tissue up 20% 32 , 33 due to complete dehydration from tissue. As such, multiple sections were selected from four different tissue levels (levels 1, 11, 25, and 35) among 50 serial sections, morphology of which was in keeping with the corresponding selected MRI slice (slice #7).…”