Jugular Foramen Syndrome as Initial Presentation of Metastatic Lung Cancer

Hayward, Dustin M.; Morgan, C.; Biller, Jeffrey A.; Emami, B.; Prabhu, Vinod

doi:10.1055/s-0032-1312253

Cited by 4 publications

(7 citation statements)

References 11 publications

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“…Metastatic disease is the most common cause of the JF syndrome. 18 There is usually a rapid onset of symptoms as compared with the more insidious development of symptoms seen with JF paragangliomas, schwannomas, or meningiomas. 21 …”

Section: Nonparaganglioma Jugular Foramen Tumorsmentioning

confidence: 99%

“…14 Metastatic disease in the JF is associated with rapid onset of multiple lower CN dysfunction. 18,21 There are limited data on expected outcomes of CN function after resection but given the invasive nature of metastatic lesions in the JF, preoperative neurologic dysfunction suggests a poor prognosis following resection. For radiation planning, it is recommended that dose delivered to CNs be kept lower than 60 Gy to reduce risk of CN dysfunction.…”

Section: Cranial Neuropathymentioning

confidence: 99%

“…17 Involvement of the skull base has been estimated to occur in approximately 4% of cases of systemic malignancy. 18 Adenocarcinomas that are metastatic to the JF usually originate from the prostate, breast, kidney, or lung. 19 …”

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confidence: 99%

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Nonparaganglioma Jugular Foramen Tumors

Thomas

Wiggins

Gurgel

2015

Otolaryngologic Clinics of North America

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Section: Nonparaganglioma Jugular Foramen Tumorsmentioning

confidence: 99%

Section: Cranial Neuropathymentioning

confidence: 99%

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Nonparaganglioma Jugular Foramen Tumors

Thomas

Wiggins

Gurgel

2015

Otolaryngologic Clinics of North America

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“…Metastatic involvement of cranial base is seen in only 4% of patients with systemic malignancies. The breast, lung, and prostate malignancies are shown to have a tendency to metastasize to the structures of cranial base [2]. Being only 3.5% of all cranial base metastases, jugular foramen involvement is very uncommon among the other cranial base structures [3].…”

Section: Discussionmentioning

confidence: 99%

Metastasis of lung cancer in jugular foramen: a case report

2019

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Jugular foramen tumors are uncommon cranial base lesions that cause difficulties not only in diagnosis but in treatment as well. Paraganglioma is the most common tumor involving this region. Other common tumors arising in the jugular foramen are meningiomas, schwannomas and chondrosarcomas. Metastatic involvement of this location is rare. We present a case of metastasis of lung adenocarcinoma in jugular foramen presented with cranial neuropathy. Although it is rare, metastasis of a systemic malignancy should always be considered in the differential diagnosis of a mass involving jugular foramen.

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“…There are several variations of jugular foramen syndrome related to the location of the skull base mass including Jackson syndrome (dysfunction of cranial nerves X, XI, and XII), Tapas syndrome (dysfunction of cranial nerve X and XII), Collet–Sicard syndrome (dysfunction of cranial nerves IX, X, XI, and XII), and Villaret syndrome (dysfunction of cranial nerves IX, X, XI, and XII, as well as the cervical chain sympathetics) . Classic jugular foramen, or Vernet syndrome, with occipital pain and cranial nerve IX, X, and XI involvement, is usually because of an intracranial tumor, whereas the other syndromes described are more likely to be due to an extracranial tumor …”

Section: Discussionmentioning

confidence: 99%