Juniper tar (cade oil) poisoning in new born after a cutaneous application

Feverish Agitation Unveiling a Poly Poisoning in Young Children

“…Koruk et al [2] reported the presence of renal failure (urea=114 mg/dl, serum creatinine=4.7 mg/dl) in a man who ingested a spoonful of extract of Juniperus oxycedrus in order to cure his nephrolithiasis. In our patient, hepatic enzymes showed only mild elevation and returned to normal levels on the sixth day, and there was normalization of the urea and creatinin levels 72 hours later [3].…”

Plant toxins and acute medicinal plant poisoning in children: A systematic literature review

“…Medical records have shown that acute poisoning of the cade oil may also manifest as convulsions, acute pulmonary edema, renal failure, and hepatotoxicity. [ 17 ] On the other hand, intoxication following oral ingestion of jimson weed ( Datura stramonium ) is reported from Asia, Africa, America, and Europe. Studies have also shown that Salvia officinalis (sage oil) is an epileptogenic plant, and even a single-ingested dose of this plant can cause seizure.…”

“…[ 13 14 15 ] Toxicological studies of medicinal herbs on animal models have shown that some of these plants such as daouri and juniper tar that are typically used to treat chronic eczema and other skin diseases may have nephrotoxicity or hepatotoxicity, suggesting that the use of these plants particularly in children should be reevaluated. [ 16 17 ] Although it has been shown that natural or complementary and alternative medicines, particularly medicinal plants, have fewer side effects than chemical drugs, studies have shown that herbal medicines are not all safe for direct human use, especially in pediatric patients. [ 18 19 ] The importance of acute poisoning is greater in children and especially neonates since their digestive and immune systems are not completely evolved.…”

Pharmacological and pharmaceutical technological overview for seborrheic dermatitis: a review about topical application and new approaches

“…This drug enters the combination of shampoos prepared for this therapeutic purpose. 33 Ketoconazole: It is an antifungal drug included in the imidazole group. Ketoconazole is the only drug that is capable of inhibiting the synthesis of adrenal steroids at higher doses than the doses required for antifungal activity.…”