AimsThis article aimed to examine the concept of safeguarding adults and establish an operational definition for application to practice, research and policy.DesignRodgers' evolutionary and inductive method of concept analysis was used.Data SourcesA systematic search was conducted across four electronic databases, CINAHL, PsycINFO, Scopus and PubMed, covering the period from January 2014 to May 2023. This systematic database search aimed to gather a broad spectrum of research and scholarly literature to inform and support the concept analysis. A total of 10 peer‐reviewed articles were reviewed using a data chart to identify the context, definitions, antecedents, attributes and consequences of safeguarding adults.ResultsThe analysis of the included articles helped to develop a better understanding of safeguarding adults by offering a practical operational definition tailored to the specific needs of practising nurses. The implications for practice, research and policy are discussed, highlighting the potential for improving the quality of care and ensuring the well‐being of adults at risk of abuse.ConclusionBy employing Rogers' evolutionary concept analysis method, we developed a deeper insight into safeguarding adults in health care. A synthesis of literature revealed the intricate layers and adaptations within safeguarding practices. This concept analysis lays the groundwork for future research, policy development and educational initiatives, enhancing the well‐being and safety of adults at risk of abuse within care.ImpactBy undertaking a concept analysis of the term safeguarding adults' nurses can be more prepared to engage in and reinforce the key principles of safeguarding adults, providing guidance to ensure the protection and well‐being of adults at risk of abuse.Patient or Public ContributionNot applicable.What this Paper Contributes to the Wider Body of KnowledgeThis concept analysis helps to define and clarify the conceptual term ‘safeguarding adults’ promoting a shared understanding of the key components of adult protection and providing a comprehensive framework for assessment and management of adults at risk of abuse in this field of practice.