Juvenile granulosa cell tumour: a rare clinical entity

Reddy, Kaliki Hymavathi; Pavithra, Dhayalan; Ragini, R; Pallavi, SK

doi:10.5455/2320-1770.ijrcog20141259

Cited by 2 publications

(3 citation statements)

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“…In immunohistochemical analysis, all subgroups of GCT has expressed vimentin, cytokeratins [20]. Vimentin positivity has been shown to help differentiate well-differentiated tumors from poorly differentiated ones [11]. Only one patient in this study had positive vimentin in the pathology report, and recurrence was observed in this patient.…”

Section: Discussionmentioning

confidence: 62%

“…Ovarian cancers are the fourth most seen cancer in women after breast, lung and colorectal cancer [10]. Primary ovarian malignancies are originated in three subgroups according to cells they originate from: tumors of ovarian surface epithelium, germ cells, and sex cord cells [11]. GCT are the most common type of sex cord-stromal cell tumors (SCST) [1].…”

Section: Discussionmentioning

confidence: 99%

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Juvenile granulosa cell tumor: 20 years’ experience of a Tertiary Center

et al. 2022

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Objectives:The aim of this study is to share of the 20-year experience of a tertiary center about juvenile granulosa cell tumor (JGCT) and describe clinic manifestations, treatment, and outcome of patients who diagnosed JGCT. Material and methods:Five patients who diagnosed juvenile granulosa cell tumor between 2000 and 2020 were included in the study. The demographics, clinical findings and outcomes were retrospectively evaluated. Of the 5 patients in our study, one was in the premenarcheal girl. The common complaint in all of our patients was abdominal swelling. In preoperative imaging methods, all patients had unilateral adnexal mass and no signs in favor of metastasis. All patients were staged according to FIGO classification for ovarian tumors; 3 of patients had stage IA disease, one of patients had stage IC1 and one of patients had stage IC2. All patients underwent different surgecal procedures which is appropriate for their clinical manifestations. In addition to surgery 2 patients received adjuvant chemotherapy. Results:The median follow-up period of the patients was 60 mounts and recurrence was observed in two patients who were reoperated. We have no patients who died due to this disease. Conclusions:Possible diagnosis of juvenile granulosa cell tumor should be kept in mind in a patient of young age with unilateral adnexal mass with benign features.

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Section: Discussionmentioning

confidence: 62%

Section: Discussionmentioning

confidence: 99%

Juvenile granulosa cell tumor: 20 years’ experience of a Tertiary Center

et al. 2022

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“…She presented with complaints of secondary amenorrhoea and pelvic mass and as she had stage I disease, unilateral salpingooophorectomy was done. 5 Most of the androgenic juvenile GCTs are solid in consistency with lack of classical histopathological picture of adult type GCTs. Kumar et al reported a very rare case of androgenic cystic juvenile GCT in a young girl with pelvic mass associated with secondary amenorrhea and virilization.…”

Section: Discussionmentioning

confidence: 99%