Juvenile Nasopharyngeal Angiofibroma

Garça, Mehmet Fatih; Yuca, Sevil Arı; Yuca, Köksal

doi:10.29333/ejgm/82897

Cited by 24 publications

(39 citation statements)

References 22 publications

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“…The mass is well defined, non-encapsulated and lobulated with epicenter around sphenopalatine foramina. There is intense enhancement seen because of the high vascular contents [6,7]. There is resorption or remodeling of the bone rather than the destruction which makes it different from aggressive and malignant pathologies.…”

Section: Discussionmentioning

confidence: 99%

Clinico-radiological evaluation of Juvenile Nasopharyngeal Angiofibromas: two case reports

Sharma¹,

Sharma²,

Sharma³

et al. 2017

EJMCR

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Section: Discussionmentioning

confidence: 99%

Clinico-radiological evaluation of Juvenile Nasopharyngeal Angiofibromas: two case reports

Sharma¹,

Sharma²,

Sharma³

et al. 2017

EJMCR

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“…This lack of muscle, elastic fibers is the cause for massive hemorrhage even with slight manipulation at the tumor site. 5 Patients typically present with progressive nasal obstruction (80-90%), recurrent epistaxis (40%), swelling of the cheek as seen in this case report. Headache and facial pain may arise due to involvement of para nasal sinuses.…”

Section: Discussionmentioning

confidence: 87%

Multidetector Computed Tomography Evaluation of Juvenile Nasopharyngeal Angiofibroma

Somayaji¹,

Talwade²,

Shukla³

et al. 2016

The Journal of Medical Sciences

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Juvenile nasopharyngeal angiofibroma is relatively uncommon accounting for 0.5% of all head and neck tumors occurring exclusively in adolescent males. It is a microscopically benign, yet locally aggressive tumor with high rates of recurrence and results in severe morbidity. Diagnosis requires high index of suspicion as it mimics other sinonasal conditions, like sinonasal polyp, neurofibroma, nasopharyngeal carcinoma, etc. A case of 14-year-old boy with history of swelling in the right cheek, bilateral nasal obstruction, epistaxis, and watering from right eye referred for multidetector computed tomography is reported in this study. Source of support: Nil Conflict of interest: None INTRODUCTIONJuvenile nasopharyngeal angiofibroma (JNA) is a benign, vascular, and fibrous neoplasm arising in the nasopharynx accounting for 0.5% of all head and neck tumors. It almost always occurs exclusively in adolescent males. The tumor exhibits a strong tendency to bleed and frequently exhibits destructive and aggressive behavior.1,2 It wasHippocrates who first described it in the 5th century bc. However, Friedberg first used the term angiofibroma in 1940. The diagnosis of this condition requires a high index of suspicion as it mimics other sinonasal conditions and approaching it as such may result in fatal outcome. 2 We present a case of JNA and discuss the steps necessary for radiological diagnosis using multidetector computed tomography (MDCT). CASE REPORTA 14-year-old boy presented with complaints of swelling in right cheek since 1 month, which progressively increased in size (Fig. 1). Patient also complained of bilateral nasal obstruction with history of 3 to 4 episodes of epistaxis in the last month. Patient gave history of watering from right eye. On examination, right nasal cavity showed an ulcerative growth with dilated blood vessels and serosanguinous discharge along with a swelling involving the right buccal mucosa extending to the soft and hard palate (Fig. 2)

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“…Radiation may lead to complications such as growth retardation, temporal lobe radionecrosis, keratopathy and potential carcinogenic side-effects. 6,12,13 Chemotherapy is not very effective. 6 As JNA growth is androgen-dependent, antiandrogen therapy decreases the size and vascularity of the tumour.…”

Section: Discussionmentioning

confidence: 99%

“…12,14 There have been conflicting recommendations in different studies with regard to flutamide, an androgen receptor blocker, which has been found to have unproven efficacy. However, it is of particular interest in partial volume reduction.…”

Section: Discussionmentioning

confidence: 99%

“…The transarterial technique of embolisation is associated with a significant risk of complications, such as numbness, facial palsy, strokes and occlusion of the ophthalmic artery. 6,12 Recently, the injection of embolising material by direct tumoural puncture was advocated as it produces a greater degree of tumour devascularisation than the transarterial technique. 20 Apart from numbness, facial palsy, strokes and occlusion of the ophthalmic artery, minor side-effects like pain, increased leucocyte count and fever are more common, and may mimic acute infection in the preoperative period.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Anaesthetic management of endoscopic resection of juvenile nasopharyngeal angiofibroma: our experience and a review of the literature

Khanna

Ray

Saxena

et al. 2013

Southern African Journal of Anaesthesia and Analgesia

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Juvenile Nasopharyngeal Angiofibroma

Abstract: Review of the literature was performed to define the optimal treatment of patients with juvenile nasopharyngeal angiofibroma (JNA

Cited by 24 publications

References 22 publications

Clinico-radiological evaluation of Juvenile Nasopharyngeal Angiofibromas: two case reports

Clinico-radiological evaluation of Juvenile Nasopharyngeal Angiofibromas: two case reports

Multidetector Computed Tomography Evaluation of Juvenile Nasopharyngeal Angiofibroma

Anaesthetic management of endoscopic resection of juvenile nasopharyngeal angiofibroma: our experience and a review of the literature

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