Juvenile nasopharyngeal angiofibromas in Denmark 1981–2003: diagnosis, incidence, and treatment

Glad, Henrik; Vainer, Ben; Buchwald, Christian von; Petersen, Bodil Laub; Theilgaard, Sune A.; Bonvin, P; Lajer, Christel; Jakobsen, Jørn Skibsted

doi:10.1080/00016480600818138

Cited by 99 publications

(81 citation statements)

References 23 publications

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“…71.42% in age group 11-20 & mean age 17.28 y. In the study carried out by Glad H et al, [7], median age was 15 y(range 10-24), whereas in the study carried out by Alfredo Lara Gaillard et al, [8], mean age was 16.8 y (range 9-23 y) which is similar to our results sex distribution: Angiofibroma was found only in males which correlate with literature. In the study carried out by Glad H et al, [7] and Alfredo Lara Gaillard et al, [8], all cases were found in males as in our study.…”

Section: Incidence Of Different Types Of Tumoursmentioning

confidence: 99%

Clinicopathological Profile of Benign Soft Tissue Tumours: A Study in a Tertiary Care Hospital in Western India

Ramnani

Kumar

Chandak

et al. 2014

JCDR

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Section: Incidence Of Different Types Of Tumoursmentioning

confidence: 99%

Clinicopathological Profile of Benign Soft Tissue Tumours: A Study in a Tertiary Care Hospital in Western India

Ramnani

Kumar

Chandak

et al. 2014

JCDR

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“…discussion JNA is a rare entity with an incidence reported to be approximately 0.4 cases per million, and it predominantly affects adolescent boys. 13 These tumors typically present with epistaxis, nasal obstruction, and a nasopharyngeal mass.…”

Section: Case 1: Ipsilateral Endoscopic Endonasal Approach (Uninostrimentioning

confidence: 99%

Endoscopic graduated multiangle, multicorridor resection of juvenile nasopharyngeal angiofibroma: an individualized, tailored, multicorridor skull base approach

Liu

Husain²,

Kanumuri³

et al. 2016

JNS

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OBJECT Juvenile nasopharyngeal angiofibromas (JNAs) are formidable tumors because of their hypervascularity and difficult location in the skull base. Traditional transfacial procedures do not always afford optimal visualization and illumination, resulting in significant morbidity and poor cosmesis. The advent of endoscopic procedures has allowed for resection of JNAs with greater surgical freedom and decreased incidence of facial deformity and scarring. METHODS This report describes a graduated multiangle, multicorridor, endoscopic approach to JNAs that is illustrated in 4 patients, each with a different tumor location and extent. Four different surgical corridors in varying combinations were used to resect JNAs, based on tumor size and location, including an ipsilateral endonasal approach (uninostril); a contralateral, transseptal approach (binostril); a sublabial, transmaxillary Caldwell-Luc approach; and an orbitozygomatic, extradural, transcavernous, infratemporal fossa approach (transcranial). One patient underwent resection via an ipsilateral endonasal uninostril approach (Corridor 1) only. One patient underwent a binostril approach that included an additional contralateral transseptal approach (Corridors 1 and 2). One patient underwent a binostril approach with an additional sublabial Caldwell-Luc approach for lateral extension in the infratemporal fossa (Corridors 1–3). One patient underwent a combined transcranial and endoscopic endonasal/sublabial Caldwell-Luc approach (Corridors 1–4) for an extensive JNA involving both the lateral infratemporal fossa and cavernous sinus. RESULTS A graduated multiangle, multicorridor approach was used in a stepwise fashion to allow for maximal surgical exposure and maneuverability for resection of JNAs. Gross-total resection was achieved in all 4 patients. One patient had a postoperative CSF leak that was successfully repaired endoscopically. One patient had a delayed local recurrence that was successfully resected endoscopically. There were no vascular complications. CONCLUSIONS An individualized, multiangle, multicorridor approach allows for safe and effective surgical customization of access for resection of JNAs depending on the size and exact location of the tumor. Combining the endoscopic endonasal approach with a transcranial approach via an orbitozygomatic, extradural, transcavernous approach may be considered in giant extensive JNAs that have intracranial extension and intimate involvement of the cavernous sinus.

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“…The most common presentation is unilateral nasal obstruction, followed by epistaxis. 9 Most patients do not have any associated systemic illness. A CT scan and MRI play a critical role in proper evaluation of the tumour.…”

Section: Discussionmentioning

confidence: 99%

Anaesthetic management of endoscopic resection of juvenile nasopharyngeal angiofibroma: our experience and a review of the literature

Khanna

Ray

Saxena

et al. 2013

Southern African Journal of Anaesthesia and Analgesia

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Juvenile nasopharyngeal angiofibromas in Denmark 1981–2003: diagnosis, incidence, and treatment

Cited by 99 publications

References 23 publications

Clinicopathological Profile of Benign Soft Tissue Tumours: A Study in a Tertiary Care Hospital in Western India

Clinicopathological Profile of Benign Soft Tissue Tumours: A Study in a Tertiary Care Hospital in Western India

Endoscopic graduated multiangle, multicorridor resection of juvenile nasopharyngeal angiofibroma: an individualized, tailored, multicorridor skull base approach

Anaesthetic management of endoscopic resection of juvenile nasopharyngeal angiofibroma: our experience and a review of the literature

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