Juvenile polyps of the colon and rectum

Roth, Sanford I.; Helwig, Elson B.

doi:10.1002/1097-0142(196304)16:4<468::aid-cncr2820160408>3.0.co;2-f

Cited by 138 publications

(30 citation statements)

References 27 publications

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“…Until a total colonoscopy was performed on patients suspected of having polyps, it was generally accepted that juvenile colorectal polyps are solitary and that up to 90% are found in the rectosigmoid colon. [14][15][16] However, in recent studies, two or more polyps were present in 24-58% of patients, with 15-60% of polyps located proximal to the splenic flexure. 3,6,11,17 A prior study 18 showed that 94.4% of juvenile polyps were found in the rectum and rectosigmoid colon, and 12.5% of the cases had multiple polyps.…”

Section: Discussionmentioning

confidence: 97%

Is Colonoscopy Necessary in Children Suspected of Having Colonic Polyps?

Lee¹,

Lee²,

Lee³

et al. 2010

Gut Liver

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Section: Discussionmentioning

confidence: 97%

Is Colonoscopy Necessary in Children Suspected of Having Colonic Polyps?

Lee¹,

Lee²,

Lee³

et al. 2010

Gut Liver

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“…Le pH des incubations rend pratiquement inefficaces les nucleases neutres et alcalines [14-191 mais il permet b des isoenzymes acides non lysosomaux comme la ribonuclease soluble [20], la phosphatase soluble anionique et thermolabile [21] et la p-glucuronidase microsomale [ 11,221 d'exercer Bventuellement leurs effets.…”

Section: Mesure Des Activitds Enxymatiquesunclassified

Hydrolases acides hepatiques en fin de malnutrition protidique chez le rat

1968

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The free and total activities of four acid hydrolases were assayed in the liver of young rats during the 3 days period following the end of a lysine and threonine deficiency.1. There is a slight decrease at 15 h in the total activities of deoxyribonuclease, ribonuclease, P-glycerophosphatase and 8-glucuronidase, on a wet weight tissue basis. These activities get back to starting values later on, except for deoxyribonuclease which has risen by a factor of 1.8 after 3 days.2. Free activities expressed as percentages of total activities increase more or less rapidly and steadily during the recovery period. The free activity of deoxyribonuclease has augmented after 2 and 3 days; that ofb-glucuronidase rises already after 15 h and stays elevated for 3 days; that of the other hydrolases is above the starting level only at the end of the first day.3. These data suggest a labilization of the lysosomes and a net synthesis of acid deoxyribonuclease. The possible effects of these modifications of hepatic lysosomes on the first mitotic wave and on the other cellular alterations which follow the end of protein malnutrition are discussed.La fin d'une carence de trois semaines en lysine et en threonine provoque, dans le foie du jeune rat, le developpement d'une vague mitotique assez bien synchronisee qui se manifeste avec un maximum d'intensit6 au deuxieme jour de la r6alimentation) apr& une recharge d6jA substantielle des h6patocytes en RNA et proteines [1-31.Nous avons prkcis6 prec6demment comment 6voluent) pendant les 72 h qui suivent la fin de la malnutrition, les activit6s enzymatiques suivantes, impliqu6es dans le mktabolisme du DNA: la thymidine kinase, la dTMP kinase, la dTMP phosphatase acide, la thymidine phosphorylase et la 4,5-dihydrothymine dkshydrog6nase.I1 nous a paru int6essant d'etudier biochimiquement le comportement des lysosomes pendant la m6me periode car les auteurs qui Btudient la prolif6ration des h6patocytes aprhs hepatectomie partielle constatent des modifications dans la localisation et la

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“…5 The youngest reported patient is the patient reported herein, who was 1 year old at the time of presentation. Female patients are two times more common than male ones.…”

Section: Discussionmentioning

confidence: 90%

Nonfamilial Juvenile Polyposis Coli in a Child: Report of a Case

et al. 2004

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Juvenile polyposis coli (JPC) is an uncommon condition, manifesting as hamartomatous gastrointestinal polyposis with potential malignancy. This report describes a 15-month-old girl who was diagnosed to have nonfamilial JPC accompanied by macrocephaly, clubbed fingers, and mental retardation. Radiography of the colon by a barium enema and total colonoscopy demonstrated numerous colonic polyps. A barium meal study did not show any abnormality in the stomach, duodenum, or small intestine. She died at 6 years of age from hemorrhagic shock due to massive lower gastrointestinal bleeding associated with a rectal prolapse. The related literature is reviewed, and the treatments and complications of JPC in children are also discussed. We emphasize that family members of patients diagnosed with juvenile polyposis should be questioned and undergo appropriate examinations of the entire intestine from the stomach to the rectum.

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Juvenile polyps of the colon and rectum

Cited by 138 publications

References 27 publications

Is Colonoscopy Necessary in Children Suspected of Having Colonic Polyps?

Is Colonoscopy Necessary in Children Suspected of Having Colonic Polyps?

Hydrolases acides hepatiques en fin de malnutrition protidique chez le rat

Nonfamilial Juvenile Polyposis Coli in a Child: Report of a Case

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