Juvenile Psammomatoid Ossifying Fibroma (JPOF) of Maxilla—a Rare Entity

Abstract

Juvenile Ossifying Fibroma (JOF) is an uncommon fibro-osseous lesion affecting the facial bones. Although a benign entity, JOF is known to be locally aggressive and has a high tendency to recur. Two distinctive microscopic patterns have been described; a trabecular variant and a Psammomatoid variant. The latter variant is predominantly a craniofacial lesion and occurs rarely in the jaws. We report a rare case of Psammomatoid Juvenile ossifying fibroma that occurred in maxilla of a 20 year old female patient.

Psammomatoid juvenile ossifying fibroma: Report of three cases with a review of literature

“…It is differentiated from fibrous dysplasia by its relatively well-delineated border from the surrounding tissue, as seen in the present cases. [ 8 10 ] Aggressive lesions with marked destruction of adjacent structures mimic osteosarcoma radiographically; the lack of periosteal reaction in JOF helps in differentiation.…”

A massive sinonasal psammomatoid variant of juvenile ossifying fibroma: Report of a rare entity

“…[ 1 2 ] Sclerotic changes are evident in the lesion which may show a ground-glass appearance. [ 4 ] The present case revealed mixed radiolucent and radiopaque areas associated with the lesion.…”

“…Benjamins in 1938 first reported PsJOF as an “osteoid fibroma with atypical ossification of the frontal sinus”,[ 4 ] Golgi in 1949 called it as “Psammomatoid Ossifying Fibroma”,[ 2 ] and Johnson in 1952 coined the term “Juvenile Active Ossifying Fibroma”. [ 2 4 ] According to WHO classification of odontogenic tumors 2005, it was named as “Juvenile Psammomatoid Ossifying Fibroma”. [ 2 ] The term juvenile psammomatoid ossifying fibroma is now used to designate the neoplasm of the craniofacial skeleton of young age with well-defined clinicopathological features.…”

“…The pathogenesis of these jaw lesions are related to the abnormal development of basal generative mechanism that is essential for root formation. [ 4 ] This paper highlights a rare entity of PsJOF involving the maxillary sinus and nasal cavity on the left side. Radiological and histological features along with the treatment have been discussed avidly.…”

Psammomatoid juvenile ossifying fi broma: Case report with management

“…In contrast the psammomatoid pattern forms concentric lamellated and spherical ossicles that vary in size and demonstrate a central basophilic area with peripheral eosinophilic rims forming brush borders that blend into the adjacent stroma. Golg (1949) [9] was the fi rst to term these spherical calcifi ed structures. The term is derived from the Greek word psammos meaning "sand."…”