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Çoban, Mehmet Zülfü; Gündüz, Fatih; Demirol, Ferhat; Örnekçi, Gürel Nedim; Karakaya, Gökhan; Türkgülü, İbrahim; Alp, Ahmet

doi:10.4194/1303-2712-v13_2_04

Cited by 4 publications

(3 citation statements)

References 10 publications

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“…Capoeta has a wide geographical range of distribution in Asia, including South China, North India, Afghanistan, Turkestan, the Aral Sea, the Middle East and Anatolia (Türkmen et al, 2002). Monitoring studies detected 18 Capoeta species in the inland waters of the Middle East (Coban et al, 2013). Among them, the Tigris scraper Capoeta umbla (Heckel, 1843) is one of the species that is overconsumed by people and has some economic value.…”

Section: Introductionmentioning

confidence: 99%

“…C. umbla inhabits the Euphrates -Tigris river systems. It is also locally known as a "lake fish" or "stream fish" and it is the most commercially valued fish for the local people (Canpolat & Calta, 2001;Türkmen et al, 2002;Coban et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

“…In spite of the well studied toxicity of copper ions, the cytotoxic effects of different intake doses of copper in the fish brain remain unknown as well as the safe dosage of this chemical for fish farming. C. umbla is tolerant and adapted to varying environmental conditions (Coban et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

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Sublethal doses of copper sulphate initiate deregulation of glial cytoskeleton, NF-kB and PARP expression in Capoeta umbla brain tissue

Kırıcı

Nedzvetsky

Gasso

2019

Regul. Mech. Biosyst.

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Copper sulphate pentahydrate (CuSO4∙5H2O) is widely used as a pesticide not only in agricultural but in aquaculture farming as well. Copper sulphate is a cheap chemical and able to contaminate the environment, especially water sources, which is crucial for fish harvesting and farming. The copper contamination in some areas is caused over decades because this pesticide has long been used everywhere. Copper ions inhibit invasive aquatic plants and many microorganisms but contaminate soil and natural water resources. The family of copper-containing chemicals is frequently used as algaecides in swimming pools. Despite the high toxicity of copper ions for fish in freshwater ponds, copper sulphate remains one of the prevalent pesticides in fish farming everywhere. High cytotoxicity and accumulation of the copper ions in sediments require study and calculation of the optimal dosage for its use as an antiseptic agent which will not have a detrimental effect on various tissue types of aquatic organisms. The main recognized mechanism which accompanies the toxic effect of copper ions is the generation of oxidative stress. Neural tissue cells are extremely susceptible to oxidative damage and the functions of the CNS are critical to the vitality of organisms. Glial cells maintain the structure and many vital functions of neurons. The cytoskeleton glial fibrillary acidic protein (GFAP), transcriptional nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kB) and Poly(ADP-ribose) polymerase (PARP) are critical participants in a cellular response to a toxic agent impact. As this takes place, it could be applied in biomarking of heavy metal toxicity. In the presented study, we investigated the effects of copper ions on PARP, NF-kB, and GFAP expression in the Tigris scraper Capoeta umbla brain tissue. For 96 hours the fish were exposed to copper sulphate at sublethal concentrations, namely 1/2, 1/4 and 1/8 of the LD50 value. Western blot analysis of GFAP and PARP was used to assess further effects in the brain tissue. Every studied dose of copper significantly downregulated the expression of GFAP after 72 hours of treatment. In spite of the common increment in the GFAP content, 48 hours exposure to copper initiated the upregulation of that cytoskeleton marker. Moreover, treatment with copper sulphate induced several changes in the β-actin level, especially in the fish group treated for 72 hours. The observed effect of copper in the fish brain evidences the unspecific toxic effect of the copper ions in the brain tissue cells. The obtained results demonstrated meaningful disturbance in the expression of transcriptional factor NF-kB in the brain of the fish group exposed to copper. The changes found in the fish brain indicate the dose-dependent effect in a concentration range 185–740 µg/L of copper sulphate during 72 hours. However, the exposure to low dose of copper ions showed no effect in the fish group treated for 24 hours. Comparative analyses of the PARP content in the brain of fish exposed to copper for 72 hours was significantly less than in the groups treated with copper for both 24 and 48 hours. Thus, the copper ions in the dose range 185–740 µg/L can suppress PARP expression in a time-dependent manner. The results showed that copper ions could induce astroglial response accompanied by modulations of NF-kB and PARP-1 expression. The data obtained in this study suggest that copper sulphate has a significant effect on astrogliosis and DNA damage in the fish brain.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Sublethal doses of copper sulphate initiate deregulation of glial cytoskeleton, NF-kB and PARP expression in Capoeta umbla brain tissue

Kırıcı

Nedzvetsky

Gasso

2019

Regul. Mech. Biosyst.

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Özlüce Baraj Gölü (Elazığ-Bingöl)’nde Yaşayan Capoeta umbla (Heckel, 1843)’nın Bazı Populasyon Parametreleri

Eroğlu

Düşükcan²,

Çoban³

2018

Kahramanmaraş Sütçü İmam Üniversitesi Doğa Bilimleri Dergisi

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Bu çalışma, Ekim 2015-Mart 2016 tarihleri arasında Elazığ ve Bingöl il sınırları içerisinde bulunan Özlüce Baraj Gölü'nde gerçekleştirilmiştir. Çalışmada toplam 376 adet (153 erkek, 223 dişi) Capoeta umbla (Heckel, 1843) örneği incelenmiş, örneklerin I-XII yaş grupları arasında dağılım gösterdiği ve dişi:erkek oranının 1:1,46 olduğu belirlenmiştir. Total boylar (TL) erkek bireylerde 15,9-39,7 cm ve dişi bireylerde 18,1-46,7 cm; total ağırlıklar (W) erkeklerde 35,0-592,9 g ve dişilerde 48,0-1190,0 g; kondisyon faktörleri ise erkeklerde 0,672-1,544, dişilerde ise 0,541-1,494 arasında değişmiştir. Boy-ağırlık ilişkileri erkeklerde W= 0,0066*TL 3,0928 (R 2 =0,95), dişilerde W= 0,0072*TL 3,0644 (R 2 =0,89) ve populasyon genelinde ise W= 0,0071*TL 3,0702 (R 2 =0,94) olarak tespit edilmiştir. von Bertalanffy büyüme parametreleri (VBBD)

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Some Growth Parameters of Capoeta umbla (Heckel, 1843) Population Living In The Pülümür River

Özcan

Serdar

2021

International Journal of Pure and Applied Sciences

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In this study, some growth parameters have been investigated like sex distribution, length and weight relationship, age determination, von Bertalanffy growth parameters and condition factor of Capoeta umbla (Heckel, 1843) (644 female, 743 male) captured from Pülümür River between 2017 and 2019. Females varied from 7.1 to 38.8 cm in total length and 3.4 to 514.2 g in weight. Males varied from 7.3 to 38.3 cm in total length and 3.5 to 450.4 g in weight. The sex ratio (females/males) for C. umbla was 1:1.154. The age groups for C. umbla was 0-11. The von Bertalanffy growth parameters were determined as Lt=49. 25[1-e -0.128(t+1.68) ]; Wt=666.91[1-e -0.128(t+1.68) ] 2.973 for female, Lt=44.42 [1-e -0.155(t+1.37) ]; Wt=735.19[1-e -0.155(t+1.37) ] 2.954 for male and Lt=45.29 [1-e -0.146(t+1.42) ]; Wt=772.56[1-e -0.146(t+1.42) ] 2.963 for all individuals. The growth performance index (Ф') value was determined as 2.476. The length and weight relations of C. umbla were found as W=0.0096*L 2.973 , R 2 =0.97 (95 % CI of b=2. 773-3.139) for females; W=0.0103*L 2.954 , R 2 =0.98 (95 %CI of b=2.797-3.092) for males and W=0.0100*L 2.963 , R 2 =0.98 ) for all individuals. The growth type of C. umbla was isometric for all individuals (R=0.99, R 2 =0.97, F1,1385=51700.4, P<0.001). The highest condition factor was observed as 2nd age (0.931), while the lowest was observed 11nd age (0.796).

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Cited by 4 publications

References 10 publications

Sublethal doses of copper sulphate initiate deregulation of glial cytoskeleton, NF-kB and PARP expression in Capoeta umbla brain tissue

Sublethal doses of copper sulphate initiate deregulation of glial cytoskeleton, NF-kB and PARP expression in Capoeta umbla brain tissue

Özlüce Baraj Gölü (Elazığ-Bingöl)’nde Yaşayan Capoeta umbla (Heckel, 1843)’nın Bazı Populasyon Parametreleri

Some Growth Parameters of Capoeta umbla (Heckel, 1843) Population Living In The Pülümür River

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